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Updated: Feb 7, 2026

One-pot Microwave-assisted Conversion of Anomeric Nitrate-esters to Trichloroacetimidates
Published on: January 15, 2018
Rutas sintéticas eficientes de un solo paso asistidas por microondas para derivados de pirido[2,3-d]imidazoles
Bartosz Orwat1,2,3, Sylwia Raczak2,3, Kamila Jankowska2,3
1Department of Molecular Physics, Faculty of Chemistry, Lodz University of Technology, Żeromskiego 116Żeromskiego 116, Łódź 90-924, Poland.
Abstract:
Herein, we report efficient microwave-assisted one-pot protocols, enabling the efficient synthesis of a broad scope of functionalized pyrido[2,3-d]imidazoles. The developed methodologies allow obtaining target compounds using cheap reagents and catalysts, in very short reaction times, and perform three-step reactions in the same vessel without the need of intermediate isolation. The obtained pyridoimidazoles equipped with alkyl, alkoxy, hydroxy, halogen, acyl, and amino substituents were fully characterized and constitute useful materials for coordination chemistry or building blocks for further transformations.
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