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Localización de GATA-3 da forma a la función de los linfocitos

Philippe Saikali¹, Maria Dzamukova¹, Christina Stehle²

¹Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Rheumatology and Clinical Immunology, Experimental Immunology and Osteoarthritis Research, Berlin, Germany; German Rheumatology Research Center (DRFZ), a Leibniz Institute, Pitzer Laboratory of Osteoarthritis Research, Berlin, Germany.

|February 6, 2026

Resumen

La importación nuclear de GATA-3 controla la función de los linfocitos. El bloqueo de esta importación altera las características de las células T helper 2, lo que resalta su papel crucial en la biología de las células inmunitarias.

Palabras clave:

inmunología GATA-3 LCMV célula T helper reprogramación de células Th1 y Th2 importazola importina-β célula linfoide innata compartimentalización intracelular importación nuclear factor de transcripción

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