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Combatiendo la resistencia a los medicamentos antivirales: una estrategia multifacética

Jiao Zhou1,2, Ashim Nandi3, Yan Xu4

  • 1Ciechanover Institute of Precision and Regenerative Medicine, School of Medicine, Chinese University of Hong Kong, Shenzhen 518172, China.

Accounts of chemical research
|February 6, 2026
PubMed
Resumen

Los investigadores desarrollaron una estrategia multifacética para combatir la resistencia a los medicamentos de la proteasa viral, incluidos nuevos inhibidores y degradadores dirigidos a la proteasa principal (Mpro) de SARS-CoV-2. Este enfoque utiliza métodos computacionales e inteligencia artificial para diseñar antivirales efectivos contra mutaciones resistentes.

Palabras clave:
resistencia a antiviralesSARS-CoV-2Mproinhibidoresdegradadoresdiseño de fármacos asistido por IAmutaciones resistentes

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