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Cognitive Dissonance01:38

Cognitive Dissonance

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Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
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Elements and Compounds01:27

Elements and Compounds

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Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
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Periodic Classification of the Elements04:00

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The periodic table arranges atoms based on increasing atomic number so that elements with the same chemical properties recur periodically. When their electron configurations are added to the table, a periodic recurrence of similar electron configurations in the outer shells of these elements is observed. Because they are in the outer shells of an atom, valence electrons play the most important role in chemical reactions. The outer electrons have the highest energy of the electrons in an atom...
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Classification of Elements and Compounds02:54

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Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond. Elements are classified as atomic or molecular based on the nature of their basic units.
Compounds are pure substances composed of two or more elements in fixed, definite proportions. Compounds are classified as ionic or molecular (covalent) based on the bonds...
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Key Elements for Plant Nutrition02:35

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Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
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Elements: Chemical Symbols and Isotopes02:31

Elements: Chemical Symbols and Isotopes

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A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
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Updated: Feb 8, 2026

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
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Bioelementos circulantes y su asociación con el deterioro cognitivo

Masroor Anwar1, Javed A Qadri2, Mohd Suhail Ashar1

  • 1Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)
|February 6, 2026
PubMed
Resumen

La contaminación ambiental ha aumentado los niveles de bioelementos en pacientes indios con deterioro cognitivo (CI). Ocho elementos, incluidos el litio (Li) y el aluminio (Al), se elevaron significativamente en individuos con CI, lo que sugiere un posible vínculo con la neurotoxicidad y la detección temprana de la enfermedad.

Palabras clave:
Enfermedad de AlzheimerBioelementosDeterioro cognitivoICP-MSNeurodegeneraciónNeurotoxicidad

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Área de la Ciencia:

  • Ciencias Ambientales y Toxicología
  • Neurociencia y Neurología
  • Química Analítica

Sus antecedentes:

  • La rápida industrialización y urbanización en la India han provocado un aumento de la contaminación ambiental por bioelementos.
  • Los desequilibrios en las concentraciones de bioelementos en sangre pueden alterar la homeostasis y causar efectos neurodegenerativos.
  • Existen datos limitados sobre la asociación entre los bioelementos y el declive cognitivo.

Objetivo del estudio:

  • Realizar un perfil cuantitativo de los bioelementos circulantes en pacientes con deterioro cognitivo (CI).
  • Investigar la asociación entre las concentraciones de bioelementos específicos y el deterioro cognitivo.

Principales métodos:

  • Cuantificación de 19 elementos en 65 participantes mediante espectrometría de masas con plasma acoplado inductivamente (ICP-MS).
  • Se realizaron evaluaciones clínicas y funcionales integrales para evaluar las capacidades cognitivas.
  • Comparación de los niveles de bioelementos entre pacientes con CI y grupos de control.

Principales resultados:

  • Se observaron aumentos significativos en ocho elementos (Li, Al, V, Mn, Co, Ni, Zn, Ag) en pacientes con CI en comparación con los controles.
  • Los pacientes con deterioro cognitivo tuvieron una puntuación significativamente menor en el Mini-Examen del Estado Mental (MMSE) (13,77 ± 0,99) que los controles (27,78 ± 0,36).
  • Se cuantificaron concentraciones elevadas de Li, Al, V, Mn, Co, Ni, Zn y Ag en pacientes con CI.

Conclusiones:

  • Los bioelementos estudiados (Li, Al, V, Mn, Co, Ni, Zn, Ag) pueden formar una firma distintiva en pacientes con CI.
  • La detección de estas firmas de bioelementos en personas mayores podría ayudar en el manejo temprano de la neurotoxicidad inducida por elementos.
  • Esta investigación destaca un biomarcador potencial para la identificación temprana y la intervención en el declive cognitivo.