Video Experimental Relacionado

Updated: Feb 8, 2026

Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures
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Utilizing Functional Genomics Screening to Identify Potentially Novel Drug Targets in Cancer Cell Spheroid Cultures

Published on: December 26, 2016

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Edición epitranscriptómica basada en METTL3 para cribado identifica sitios m6A funcionales en cánceres

Xin Xu1,2, Yujuan Wang3,4, Helen Zhu3,5,6

  • 1Institute of Antibody Engineering, School of Laboratory Medicine and Biotechnology, Southern Medical University, Guangzhou, China. xinxu768@smu.edu.cn.

Nature cancer
|February 6, 2026
PubMed
Resumen

Los investigadores desarrollaron un nuevo método de cribado para mapear las modificaciones de N6-metiladenosina (m6A) en todo el transcriptoma. Identificaron 222 sitios m6A que afectan la proliferación celular, incluido un sitio supresor de tumores en CHD9 crucial para el cáncer de próstata.

Palabras clave:
epitranscriptómicam<sup>6</sup>Acáncercribado funcionalCHD9cáncer de próstata

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