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Radioterapia Adyuvante para el Cáncer de Mama sin Tatuajes: Comparación entre Imágenes de Superficie y Localización

C Lenci¹, F De Felice¹, M Tomaciello¹

¹Radiation Oncology, AOU Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Rome, Italy.

Clinical oncology (Royal College of Radiologists (Great Britain))

|February 7, 2026

Resumen

La radioterapia guiada por superficie (SGRT) ofrece una precisión y reproducibilidad superiores para el posicionamiento de la radioterapia del cáncer de mama del lado derecho en comparación con los tatuajes tradicionales. Este método no invasivo mejora la experiencia del paciente y la precisión del tratamiento.

Área de la Ciencia:

Oncología de Radiación
Física Médica

Sus antecedentes:

El posicionamiento preciso del paciente es crucial para una radioterapia (RT) eficaz en el cáncer de mama del lado derecho.
Las configuraciones convencionales basadas en tatuajes pueden causar angustia al paciente y carecer de precisión.
La radioterapia guiada por superficie (SGRT) presenta una alternativa no invasiva para la alineación del paciente.

Objetivo del estudio:

Comparar la precisión y reproducibilidad de la SGRT frente al posicionamiento convencional basado en tatuajes para la radioterapia del cáncer de mama del lado derecho.
Evaluar los errores de posicionamiento y la variabilidad entre fracciones entre los dos métodos de posicionamiento.

Principales métodos:

Diseño de estudio prospectivo multicéntrico cruzado.
Comparación de SGRT (AlignRT) y posicionamiento basado en tatuajes en 52 pacientes.
Cuantificación de los errores de posicionamiento mediante registros de tomografía computarizada de haz cónico y análisis estadístico (Shapiro-Wilk, pruebas t).

Principales resultados:

La SGRT demostró errores medios de posicionamiento significativamente menores en todas las direcciones (longitudinal, vertical, lateral) en comparación con el posicionamiento basado en tatuajes (P < 0,001 para longitudinal y vertical, P = 0,044 para lateral).
La SGRT presentó una menor variabilidad entre fracciones y menos valores atípicos (>1 cm).
Se observó una mayor estabilidad de posicionamiento con la SGRT.

Conclusiones:

La SGRT con AlignRT proporciona una mayor precisión y reproducibilidad para el posicionamiento del paciente en la radioterapia del cáncer de mama del lado derecho.
Este método no invasivo mejora la precisión del tratamiento, reduce la variabilidad del posicionamiento y mejora la comodidad del paciente al eliminar los tatuajes.
Se recomienda una mayor investigación para validar los hallazgos y evaluar los resultados a largo plazo.

Palabras clave:

Cáncer de mama SGRT calidad de vida radioterapia tatuaje

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