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Updated: Feb 9, 2026

DNA-affinity-purified Chip DAP-chip Method to Determine Gene Targets for Bacterial Two component Regulatory Systems
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Refactorización de sistemas de dos componentes para la regulación regulable de la expresión génica y la detección

Sheng-Yan Chen1, Haoran Xu2, Xinyi Wan3

  • 1Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou 310058, China; ZJU-Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, Hangzhou 311215, China; School of Chemistry and Chemical Engineering, State Key Laboratory Incubation Base for Green Processing of Chemical Engineering, Shihezi University, Shihezi 832003, China.

Cell systems
|February 7, 2026
PubMed
Resumen

Este estudio refactoriza sistemas de dos componentes (TCS), revelando los reguladores de respuesta (RR) y las quinasas de histidina (HK) como clave para la programabilidad. Los sensores TCS diseñados ofrecen detección ultrasensible y un rendimiento mejorado de los biosensores.

Palabras clave:
regulación de la expresión génicabiosensor codificado genéticamenteamplificador de bajo ruidocircuito de tipo interruptorsistema de detección sinérgicasistema de dos componentes

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