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Updated: Feb 9, 2026

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Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue
Published on: October 26, 2014
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Hipotiroidismo asociado con medicamentos antiepilépticos: dos informes de casos
1Gillette Children's Hospital and Clinics, St. Paul, MN, USA.
Journal of pediatric nursing
|February 7, 2026
Resumen
Los medicamentos antiepilépticos (MAE) pueden alterar los niveles de hormonas tiroideas. El monitoreo de la función tiroidea es crucial para pacientes pediátricos en tratamiento a largo plazo con MAE para detectar posibles anomalías.
Área de la Ciencia:
- Endocrinología Pediátrica
- Farmacología
- Neurología
Sus antecedentes:
- Los medicamentos antiepilépticos (MAE) son tratamientos primarios para la epilepsia.
- No se comprenden completamente los mecanismos por los cuales los MAE afectan las hormonas tiroideas.
- La investigación existente sugiere la necesidad de monitorear las hormonas tiroideas en pacientes que usan MAE.
Objetivo del estudio:
- Informar una serie de casos de pacientes pediátricos con MAE que presentaron anomalías tiroideas.
- Destacar la importancia de la evaluación endocrinológica para la disfunción tiroidea en niños con MAE.
Principales métodos:
- Informe de caso de dos pacientes pediátricos.
- Revisión de derivaciones a clínicas de endocrinología.
- Análisis de los niveles de hormonas tiroideas en pacientes con uso a largo plazo de MAE.
Principales resultados:
- Ambas pacientes habían estado tomando MAE durante varios años.
- Las evaluaciones endocrinológicas revelaron niveles anormales de hormonas tiroideas en ambos casos.
- Los motivos de derivación fueron la salud ósea y los signos de pubertad precoz, respectivamente.
Conclusiones:
- El uso a largo plazo de medicamentos antiepilépticos puede estar asociado con anomalías en las hormonas tiroideas en pacientes pediátricos.
- Se recomienda el monitoreo regular de la función tiroidea en niños que reciben terapia con MAE.
- La evaluación endocrina es importante para identificar la disfunción tiroidea en esta población.
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