Video Experimental Relacionado

Updated: Feb 10, 2026

Confocal Microscopy to Measure Three Modes of Fusion Pore Dynamics in Adrenal Chromaffin Cells
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Conocimientos mecánicos sobre la dinámica de Orai durante la apertura de los poros

Hadil Najjar1, Veronika Aichner1, Magdalena Prantl1

  • 1Institute of Biophysics, JKU Life Science Center, Johannes Kepler University Linz, Linz, Austria.

Channels (Austin, Tex.)
|February 9, 2026
PubMed
Resumen

Los canales Orai, cruciales para la entrada de calcio (Ca2+), se activan por las proteínas STIM que detectan el agotamiento de calcio ER. Esta revisión detalla los cambios conformacionales y las interacciones moleculares que rigen el encierro del canal Orai1 y la permeación iónica.

Palabras clave:
Los canales iónicos, SOCE.Orai1o1o1o1o1o1o1o1o1o1o1o1o1o1o1o1o1El STIM1 es el STIM1.el calcio (Ca2+), los canales CRAC.sitios de contacto del dominio inter- y intra-transmembrana, hidratación, expansión del código genético, enlaces cruzados.Dinámica de las proteínas Dinámica de las proteínas

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