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Factores de riesgo para complicaciones postoperatorias después de la esplenectomía en la enfermedad de Wilson: un
Xiuquan Shi1,2,3, Sihuan Zhu1,2, Hui Peng1,2
1The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, China.
Resumen
La esplenectomía en pacientes con enfermedad de Wilson tiene una alta tasa de complicaciones (68,7%), incluyendo sangrado y fiebre. La evaluación preoperatoria del hipersplenismo y la función hepática es crucial para la estratificación del riesgo.
Área de la Ciencia:
- Hepatología Hepatología.
- Gastroenterología y Gastroenterología.
- Oncología Quirúrgica Oncología Quirúrgica.
Sus antecedentes:
- La esplenectomía es un procedimiento común para los pacientes con enfermedad de Wilson que experimentan hipersplenismo debido a la hipertensión portal.
- Existen datos limitados a gran escala sobre las complicaciones postoperatorias después de la esplenectomía en esta población de pacientes.
Objetivo del estudio:
- Para analizar las complicaciones postoperatorias de la esplenectomía en pacientes con enfermedad de Wilson.
- Para identificar los factores de riesgo asociados con estas complicaciones.
Principales métodos:
- Análisis retrospectivo de 986 pacientes con enfermedad de Wilson que se sometieron a una esplenectomía entre 2001 y 2019.
- Análisis multivariable para determinar factores de riesgo independientes para las complicaciones postoperatorias.
Principales resultados:
- La tasa general de complicaciones postoperatorias fue del 68,7%.
- La hemorragia (29,0%), la fiebre (44,9%) y la trombosis de la vena portal (20,5%) fueron las complicaciones más frecuentes.
- El grado de hiperesplenismo, la función hepática anormal y los niveles más bajos de alanina aminotransferasa / albúmina se identificaron como factores de riesgo independientes.
Conclusiones:
- La evaluación preoperatoria de la gravedad del hipersplenismo, la función hepática y los marcadores de laboratorio es esencial.
- Esta evaluación ayuda en la estratificación del riesgo quirúrgico y la optimización de la gestión perioperatoria para los pacientes con enfermedad de Wilson sometidos a esplenectomía.
Palabras clave:
Enfermedad de Wilson La enfermedad de Wilson.El estudio de cohorte es un estudio de cohorte.complicaciones postoperatorias.factores de riesgo de los factores de riesgo.Esplenectomía Esplenectomía Esplenectomía.Más Videos Relacionados
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