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Enfermedad asociada con anticuerpos de glicoproteína de oligodendrocitos de mielina bilaterales después de la cirugía
Benjamin Besse1, Amélie Dos Santos2, Mathieu Mille2
1Department of Ophthalmology, CHU Poitiers, France.
American journal of ophthalmology case reports
|February 9, 2026
Resumen
Este informe de caso detalla una ocurrencia inusual de enfermedad asociada a anticuerpos de glicoproteína de oligodendrocitos de mielina (MOGAD) que se presenta como neuritis óptica bilateral poco después de la cirugía de cataratas. Esto pone de relieve una rara complicación postoperatoria que requiere una mayor investigación.
Área de la Ciencia:
- Oftalmología Oftalmología.
- Neuroinmunología La neuroinmunología.
- Neurología Neurología.
Sus antecedentes:
- La enfermedad asociada a anticuerpos de glicoproteínas de oligodendrocitos de mielina (MOGAD, por sus siglas en inglés) es una afección desmielinizante autoinmune.
- La neuritis óptica es una manifestación común de MOGAD, que a menudo se presenta unilateralmente.
- Las complicaciones postoperatorias después de la cirugía de cataratas pueden ser diversas, pero los eventos neuroinflamatorios son raros.
Objetivo del estudio:
- Para documentar una presentación atípica de MOGAD.
- Para describir la neuritis óptica bilateral que ocurre en el período postoperatorio temprano después de la cirugía de cataratas.
- Para resaltar una asociación potencial, aunque rara, entre la cirugía de cataratas y la aparición de MOGAD.
Principales métodos:
- Informe de caso de observación.
- Examen clínico que incluye funduscopía y angiografía con fluoresceína.
- Imágenes por resonancia magnética (IRM) de la órbita y el cerebro.
- Análisis del líquido cefalorraquídeo (LCR) y punción lumbar.
- Análisis de sangre para los autoanticuerpos de la inmunoglobulina G (IgG) MOGAD.
Principales resultados:
- Una mujer de 67 años desarrolló una disminución de la agudeza visual y dolor ocular cinco días después de la cirugía de cataratas.
- El examen del fondo reveló edema de disco óptico bilateral.
- La resonancia magnética confirmó la perineuritis óptica bilateral.
- Los análisis de sangre detectaron autoanticuerpos MOGAD IgG en un título >1: 100.
- El análisis del CSF y la presión de apertura fueron normales.
Conclusiones:
- Este caso presenta una manifestación inusual y atípica de MOGAD.
- La neuritis óptica bilateral ocurrió en la fase postoperatoria temprana de la cirugía de cataratas.
- Los hallazgos sugieren una posible asociación temporal entre la cirugía de cataratas y la presentación de MOGAD.
Palabras clave:
AION AION es el nombre que se le da a un animal.La catarata es una catarata.MOGAD es una ciudad de Mogad.Anticorpos de la glicoproteína de oligodendrocitos de mielina asociados con enfermedades asociadas con anticuerpos.NAION es el nombre de NAION.La neuritis óptica es una neuritis óptica.Más Videos Relacionados
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