Video Experimental Relacionado

Updated: Feb 10, 2026

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes

Published on: June 27, 2025

La deficiencia de vitamina D y los resultados del embarazo: evaluación basada en LC-MS / MS en el suroeste de China

Mao Zheng¹, Yali Wang¹, Ning Zou¹

¹Department of Clinical Laboratory, Deyang People's Hospital, Deyang, China.

Frontiers in medicine

|February 9, 2026

Resumen

La deficiencia de vitamina D es común en las mujeres embarazadas en Deyang, China, especialmente en el embarazo temprano. La suplementación con vitamina D3 es más efectiva que la D2.

Área de la Ciencia:

Obstetricia y Ginecología.
Endocrinología Endocrinología.
Ciencias de la Nutrición Ciencias de la Nutrición

Sus antecedentes:

La insuficiencia de vitamina D es un importante problema de salud mundial.
Las mujeres chinas embarazadas son particularmente vulnerables a la deficiencia de vitamina D.
Existen datos limitados sobre el estado de la vitamina D en el suroeste de China utilizando métodos precisos LC-MS/MS.

Objetivo del estudio:

Para investigar la prevalencia y los factores de riesgo de la deficiencia de vitamina D en mujeres embarazadas en Deyang, China.
Explorar la asociación entre la deficiencia de vitamina D y los resultados del embarazo.
Para comparar la eficacia de la suplementación con vitamina D2 y D3.

Principales métodos:

Un estudio de cohorte retrospectivo de 2.742 embarazos.
Los niveles séricos de 25(OH) D2 y 25(OH) D3 se midieron utilizando LC-MS/MS.
Los análisis de regresión logística identificaron factores de riesgo y asociaciones con los resultados.
Se evaluó la eficacia de la suplementación con vitamina D.

Principales resultados:

El 62,5% de los participantes tenían deficiencia de vitamina D (mediana de 16,3 ng/ml).
El embarazo temprano (≤12 semanas) tenía un riesgo 3,37 veces mayor de deficiencia.
La deficiencia temprana se relacionó con el hipotiroidismo gestacional (OR = 1.32).
La deficiencia tardía se asoció paradójicamente con un menor riesgo de nacimiento prematuro (OR = 0,32).
La vitamina D3 (800 UI) aumentó los niveles de 25(OH) D más que D2 (800 UI) después de un mes (+28,4 vs +14,6 ng/ml).

Conclusiones:

La deficiencia de vitamina D es prevalente en las mujeres embarazadas de Deyang, siendo el embarazo temprano un período de alto riesgo.
La deficiencia temprana es un predictor del hipotiroidismo.
La relación inversa entre la deficiencia tardía y el parto prematuro requiere más investigación.
La vitamina D3 es un suplemento más eficaz que la D2.

Palabras clave:

25 (((OH) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D) D)LC-MS/MS/MS es el mismo.los resultados adversos.embarazo embarazo embarazo embarazo embarazo embarazo embarazo La deficiencia de vitamina D es una deficiencia de vitamina D.

Más Videos Relacionados

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

The Joint Effect of Social Comparison and Social Distance on Evaluation of Intertemporal Choice Outcomes in Event-related Potential Studies

Published on: August 25, 2023

Videos de Conceptos Relacionados

Vitamins

Vitamins

Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...

Predicting Reaction Outcomes

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...

Outcomes of Glycolysis

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...

Guidelines for Writing Outcome

Guidelines for Writing Outcome

When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...

Role of Skin in Vitamin D Synthesis

Role of Skin in Vitamin D Synthesis

The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...

Mineral, Vitamin and Water Absorption

Mineral, Vitamin and Water Absorption

Electrolytes are essential minerals and ions primarily obtained from the diet and absorbed through the gastrointestinal tract. Most electrolytes are absorbed in the small intestine. While the absorption of iron and calcium primarily occurs in the duodenum, calcium is also absorbed in the jejunum and ileum. In these regions, passive diffusion contributes to its absorption alongside active transport mechanisms in the duodenum. These ions can exit the enterocytes through specialized active...