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Carcinoma de células escamosas con liquen plano hipertrófico múltiple que imita al carcinoma de células escamosas: un
Sho Hirata1, Daisuke Watabe1, Toshihide Akasaka2
1Department of Dermatology, Iwate Medical University School of Medicine, Yahabacho, Japan.
Case reports in dermatology
|February 9, 2026
Resumen
El liquen plano hipertrófico (HLP) puede imitar el carcinoma de células escamosas (SCC), lo que lleva a un diagnóstico erróneo. Una correlación clínico-patológica cuidadosa es esencial para distinguir la HLP de la SCC y evitar tratamientos innecesarios.
Área de la Ciencia:
- Dermatopatología y Dermatopatología.
- Oncología Oncología.
- Dermatología Dermatología dermatología.
Sus antecedentes:
- El liquen plano hipertrófico (HLP) con hiperplasia pseudoepiteliomática (PEH) presenta un desafío de diagnóstico.
- HLP puede ser diagnosticado erróneamente como carcinoma de células escamosas bien diferenciado (SCC).
- Menos de 26 informes de casos documentan HLP inicialmente diagnosticado erróneamente como SCC.
Objetivo del estudio:
- Para resaltar la trampa de diagnóstico de HLP imitando SCC.
- Para enfatizar la importancia de la correlación clínico-patológica en la diferenciación de HLP de SCC.
- Para agregar a la literatura limitada sobre HLP diagnosticado erróneamente como SCC.
Principales métodos:
- Presentación del caso de una mujer de 77 años con lesiones hiperqueratóticas.
- Diagnóstico inicial de SCC bien diferenciado basado en biopsia de punzón.
- La segunda biopsia reveló HLP con PEH, confirmado por hallazgos histopatológicos.
Principales resultados:
- La histopatología mostró acantosis irregular, hipergranulosis, epitelio escamoso endofítico e infiltración de la interfaz lichenoide.
- Los hallazgos fueron consistentes con HLP con PEH, no SCC, que carece de invasión destructiva.
- Las lesiones se resolvieron con clobetasol propionato tópico, sin recurrencia en 3 meses.
Conclusiones:
- HLP puede imitar de cerca bien diferenciado SCC.
- El muestreo adecuado de tejidos y la correlación clínico-patológica son cruciales para evitar diagnósticos erróneos y cirugías innecesarias.
- Las condiciones inflamatorias como el HLP deben considerarse como diagnósticos diferenciales para la sospecha de SCC.
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