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Updated: Feb 11, 2026
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Models and Methods to Evaluate Transport of Drug Delivery Systems Across Cellular Barriers
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Desbloquear el potencial de la nanotecnología en el avance de los sistemas pulmonares de administración de
Phei Er Kee1, Ching Siang Tan2, Kai Bin Liew1
1Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000 Cyberjaya, Selangor, Malaysia.
Current pharmaceutical design
|February 10, 2026
Resumen
Los sistemas de administración de fármacos pulmonares ofrecen tratamiento no invasivo para afecciones pulmonares y sistémicas. Las formulaciones de nanopartículas mejoran la estabilidad del fármaco, la orientación y la liberación para mejorar la medicina respiratoria y los resultados del paciente.
Área de la Ciencia:
- Entrega de fármacos por vía pulmonar.
- La nanotecnología en la medicina.
- Terapéutica para las vías respiratorias.
Sus antecedentes:
- Los sistemas pulmonares de administración de fármacos proporcionan administración directa a los pulmones para efectos locales o sistémicos.
- La gran superficie de los pulmones y la red alveolar permiten una rápida absorción del fármaco, reduciendo los efectos secundarios y mejorando los resultados.
- La nanotecnología mejora la estabilidad del fármaco, la captación celular, la orientación y la liberación controlada en la administración pulmonar.
Objetivo del estudio:
- Proporcionar una revisión exhaustiva de los sistemas pulmonares de administración de fármacos.
- Examinar los desafíos en la eficacia de la terapia inhalada y explorar los avances.
- Para resaltar las perspectivas futuras para la administración de fármacos pulmonares eficientes y centrados en el paciente.
Principales métodos:
- Revisión de los sistemas convencionales de administración pulmonar y sus aplicaciones.
- Análisis de los desafíos que afectan la eficacia de la terapia inhalada.
- Exploración de los avances recientes, centrándose en las formulaciones de nanopartículas.
Principales resultados:
- La administración pulmonar de fármacos permite un tratamiento dirigido con efectos secundarios sistémicos reducidos.
- La encapsulación de nanopartículas mejora la estabilidad del fármaco, la orientación y los perfiles de liberación.
- Los avances tienen como objetivo mejorar la biodisponibilidad de los medicamentos y la adherencia del paciente.
Conclusiones:
- Los sistemas de administración pulmonar basados en nanopartículas son prometedores para el tratamiento de infecciones pulmonares y sistémicas.
- Estos sistemas pueden conducir a mejores resultados para los pacientes y avanzar en la medicina respiratoria de precisión.
- Se necesita más desarrollo para estrategias de administración de fármacos pulmonares más eficientes y centradas en el paciente.
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