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Una complicación inusual en un sitio inusual: trombosis de la vena yugular interna que revela la enfermedad celíaca
Meriem Mouharir1, Zakaria Chahbi1, Hassan Qacif1
1Department of Internal Medicine, Avicenne Military Hospital - Cadi Ayyad University, Marrakesh, MAR.
Cureus
|February 10, 2026
Resumen
La enfermedad celíaca, un trastorno común que afecta a múltiples sistemas de órganos, puede manifestarse como una trombosis venosa inusual. Este caso pone de relieve la importancia de considerar la enfermedad celíaca en pacientes con eventos tromboembólicos inexplicables.
Área de la Ciencia:
- Gastroenterología y Gastroenterología.
- Hematología Hematología.
- Inmunología Inmunología.
Sus antecedentes:
- La enfermedad celíaca es un trastorno multisistémico común con diversas presentaciones clínicas.
- Cada vez se reconocen más las manifestaciones extra-digestivas, incluidos los eventos tromboembólicos.
- La trombosis venosa inexplicable puede ser una presentación rara de la enfermedad celíaca.
Objetivo del estudio:
- Para reportar un caso de trombosis venosa inusual secundaria a la enfermedad celíaca.
- Para resaltar los desafíos de diagnóstico y las implicaciones clínicas de esta asociación.
Principales métodos:
- Informe de caso de una mujer de 63 años con trombosis venosa inexplicable.
- Se realizaron exámenes clínicos, ecografía Doppler, investigaciones de laboratorio (incluida la serología) y biopsias duodenales.
- El diagnóstico de enfermedad celíaca fue confirmado por atrofia villosa (Marsh 3C).
Principales resultados:
- El paciente presentó trombosis de las venas yugulares y subclaviales internas sin factores de riesgo clásicos.
- Los hallazgos de laboratorio revelaron anemia por deficiencia de hierro y un perfil de malabsorción.
- Se confirmó la enfermedad celíaca, y el tratamiento con anticoagulantes y una dieta libre de gluten condujo a una evolución clínica favorable.
Conclusiones:
- La enfermedad celíaca debe considerarse en el diagnóstico diferencial de la trombosis venosa inexplicable, particularmente en sitios inusuales.
- El diagnóstico temprano y el tratamiento de la enfermedad celíaca pueden prevenir eventos tromboembólicos recurrentes.
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