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Updated: Feb 11, 2026

Production, Characterization and Potential Uses of a 3D Tissue-engineered Human Esophageal Mucosal Model
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La densidad y degranulación de los mastocitos de la mucosa esofágica esofágica aumentan en la enfermedad de reflujo

Tom Leech1, Madusha Peiris1

  • 1Wingate Institute of Neurogastroenterology, Blizard Institute, the Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.

American journal of physiology. Gastrointestinal and liver physiology
|February 10, 2026
PubMed
Resumen

Los mastocitos son más numerosos y activos en el revestimiento esofágico de pacientes con enfermedad de reflujo gastroesofágico (ERGE). Este aumento de la actividad de los mastocitos puede contribuir a los síntomas y la inflamación de la ERGE, lo que sugiere un potencial nuevo objetivo de tratamiento.

Palabras clave:
La Dirección General de Investigación y Desarrollo (DGBI).La degranulación es el proceso de degranulación.Enfermedad por reflujo gastroesofágico.Los mastocitos son células

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