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Enfermedad estreptocócica invasiva del grupo A en personas que experimentan falta de vivienda postpandémica en Canadá
Caroline Kassee1, Halima Dabaja-Younis2, Lucie Richard3
1Department of Microbiology, Sinai Health, Toronto, Ontario, Canada.
JAMA network open
|February 10, 2026
Resumen
Las infecciones invasivas por estreptococos del grupo A (iGAS) están aumentando entre las personas sin hogar (PEH), con una incidencia 70,7 veces mayor que en las poblaciones alojadas. Las estrategias de prevención específicas son cruciales para este grupo vulnerable.
Área de la Ciencia:
- Enfermedades infecciosas Enfermedades infecciosas.
- Epidemiología La epidemiología.
- Salud Pública La salud pública.
Sus antecedentes:
- Las infecciones invasivas por estreptococos del grupo A (iGAS) y el número de personas sin hogar (PEH) están aumentando.
- Comprender la epidemiología de las infecciones por iGAS entre las personas con PEH es crucial para desarrollar estrategias de protección efectivas.
Objetivo del estudio:
- Evaluar el impacto del resurgimiento de las infecciones por iGAS después de la pandemia de COVID-19 en PEH.
- Para comparar la incidencia, los factores de riesgo, la presentación clínica, los resultados y las cepas infectantes de iGAS entre PEH y las poblaciones alojadas.
Principales métodos:
- Un estudio transversal que utiliza datos de vigilancia iGAS basados en la población de enero de 2022 a diciembre de 2023 en Toronto y la región de Peel, Canadá.
- Se recopilaron y analizaron datos sobre el tipo de EMM, los denominadores de la población y las características clínicas.
Principales resultados:
- La incidencia de iGAS fue 70,7 veces mayor entre las personas con EPE en comparación con las personas alojadas.
- PEH tenían más probabilidades de tener iGAS presentándose como infecciones de tejidos blandos y menos probabilidades de estar inmunocomprometidos.
- Los tipos específicos de emm se asociaron desproporcionadamente con las infecciones por iGAS en PEH en comparación con las personas alojadas.
Conclusiones:
- El resurgimiento pospandémico de las infecciones por iGAS afecta significativamente a la PEH, con una mayor incidencia y características epidemiológicas distintas.
- Las diferencias en los factores de riesgo, la presentación y las cepas infecciosas resaltan la necesidad de estrategias de prevención e intervención personalizadas para la PEH.
- Se necesita urgentemente el desarrollo de una mejor protección iGAS, como vacunas, para la población PEH.
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