Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Psychology as a Science01:13

Psychology as a Science

4.0K
Psychology, as a scientific discipline, aims to understand the mind and behavior through rigorous and systematic methods. The foundation of psychological research is evidence-based, relying heavily on the scientific method to derive and validate knowledge. This structured approach ensures that findings are reliable, valid, and applicable to broader contexts.
The scientific method in psychology involves six critical steps: making observations, formulating hypotheses, conducting tests, analyzing...
4.0K
Overview of Biostatistics in Health Sciences01:19

Overview of Biostatistics in Health Sciences

5.3K
Biostatistics involves the application of statistical techniques to scientific research in health-related fields, including biology and public health. These techniques are essential for designing studies, collecting data, and analyzing it to draw meaningful conclusions. Given the complexity of biological processes, particularly in studies involving human subjects, biostatistical methods are crucial for effectively organizing and interpreting data that might otherwise obscure underlying patterns...
5.3K
What are Estimates?01:06

What are Estimates?

8.9K
It isn't easy to measure a parameter such as the mean height or the mean weight of a population. So, we draw samples from the population and calculate the mean height or mean weight of the individuals in the sample. This sample data acts as a representative measure of the population parameter. These sample statistics are known as estimates. 
The estimate for the mean of a sample is denoted by ͞x, whereas the mean of the population is designated as μ. Further, parameters such...
8.9K
Estimation of k and VD of Aminoglycosides01:20

Estimation of k and VD of Aminoglycosides

252
Aminoglycosides are a class of antibiotics used to treat various bacterial infections. Clinicians must determine the elimination rate constant (k) and volume of distribution (VD) to optimize therapeutic efficacy and minimize toxicity. The k value represents the rate at which the drug is removed from the body, and the VD reflects the degree to which the drug distributes into body tissues. Accurately estimating these parameters allows healthcare professionals to tailor drug dosing to individual...
252
Model Approaches for Pharmacokinetic Data: Physiological Models01:15

Model Approaches for Pharmacokinetic Data: Physiological Models

280
Physiological models in pharmacokinetics are instrumental in understanding the distribution and elimination of drugs within the body. These models describe the drug concentration within target organs, influenced by factors such as drug uptake, tissue volume, and blood flow. Drug uptake is governed by the partition coefficient, which signifies the drug concentration ratio in tissue to that in the blood. The blood flow rate to a specific tissue is expressed as Qt, and the rate of change in tissue...
280
Model Approaches for Pharmacokinetic Data: Compartment Models01:14

Model Approaches for Pharmacokinetic Data: Compartment Models

578
Compartmental analysis is a widely adopted approach to characterizing drug pharmacokinetics. It uses compartment models that conceptualize the body as a collection of reversibly communicating compartments, each representing a group of tissues exhibiting similar drug distribution characteristics. The movement rate of the drug between these compartments is typically described by first-order kinetics.
Two primary types of compartment models are recognized: mammillary and catenary. The more...
578

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

<sup>64</sup>Cu-Labeled Bioorthogonal Probe for Targeted Positron Emission Tomography Imaging of Malignant Melanoma.

Molecular pharmaceutics·2026
Same author

Impact of Dietary Supplement Usage on Nutrient Adequacy and the Risk of Nutrient Excess Among Korean Adults.

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association·2026
Same author

Overcrowding Stress in Livestock Production Alters Gut Microbiota Composition and Neuronal Nitric Oxide Synthase (nNOS) Expression in nNOS-HiBiT Knock-in Mouse Model.

Food science of animal resources·2026
Same author

Loss of Angptl4 Protects Mice from Intestinal Colitis and Tumorigenesis with Alternative Activation of Macrophages.

The American journal of pathology·2025
Same author

EEG-based Cross-subject Prediction for Consciousness State Transitions under Sedation using a Deep Learning Framework.

IEEE journal of biomedical and health informatics·2025
Same author

High-Performance P-type Tellurium Field-Effect Transistors by Lignin-Induced Doping.

ACS applied materials & interfaces·2025
Same journal

Mental Health in College Students: From Epidemiological Findings to Sustainable Policies.

Annual review of clinical psychology·2026
Same journal

Sex Differences in Affective Disorders: A Developmental Neuroscience Framework on the Role of Puberty.

Annual review of clinical psychology·2026
Same journal

Interpersonal Psychotherapy for the Treatment of Depression Among Adults and Adolescents.

Annual review of clinical psychology·2026
Same journal

Body-Focused Repetitive Behavior Disorders: From Competing Paradigms Toward Iterative Integration.

Annual review of clinical psychology·2026
Same journal

Assessment and Treatment of Bipolar Disorder in the Community.

Annual review of clinical psychology·2026
Same journal

Objective Assessment in Clinical Psychological Science: Progress in Wearable Alcohol Biosensors.

Annual review of clinical psychology·2026
Ver todos los artículos relacionados

Video Experimental Relacionado

Updated: Feb 12, 2026

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach
07:16

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach

Published on: April 25, 2025

819

Enfoques de estimación de modelos múltiples iterativos de grupo en la ciencia clínica.

Chaewon Lee1, Kathleen M Gates1

  • 1L.L. Thurstone Psychometric Laboratory, Department of Psychology and Neuroscience, University of North Carolina, Chapel Hill, North Carolina, USA; email: chaewon.lee@unc.edu, kmgates@unc.edu.

Annual review of clinical psychology
|February 10, 2026
PubMed
Resumen
Este resumen es generado por máquina.

Este estudio revisa la estimación del modelo múltiple iterativo de grupo (GIMME), un método para analizar datos psicológicos complejos. GIMME modela las diferencias individuales en los datos longitudinales intensivos (ILD) mientras identifica patrones generalizables.

Más Videos Relacionados

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants
06:28

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

6.3K
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

14.1K

Videos de Experimentos Relacionados

Last Updated: Feb 12, 2026

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach
07:16

Three-Dimensional Imaging of Tumor-Bearing Tissue Using the Iterative Bleaching Extends Multiplexity Approach

Published on: April 25, 2025

819
A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants
06:28

A Networked Desktop Virtual Reality Setup for Decision Science and Navigation Experiments with Multiple Participants

Published on: August 26, 2018

6.3K
Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations
12:09

Patient-specific Modeling of the Heart: Estimation of Ventricular Fiber Orientations

Published on: January 8, 2013

14.1K

Área de la Ciencia:

  • Psicología Psicología Psicología.
  • Psicología Clínica Psicología clínica.
  • Psicología Cuantitativa Psicología Cuantitativa

Sus antecedentes:

  • Los procesos psicológicos muestran una heterogeneidad significativa, desafiando los enfoques nomotéticos tradicionales.
  • Los métodos idiográficos capturan la variabilidad dentro de la persona, pero enfrentan problemas con el ruido y la generalización.
  • Los enfoques integradores equilibran las dinámicas específicas de la persona con patrones generalizables.

Objetivo del estudio:

  • Revisar la estimación del modelo múltiple iterativo de grupo (GIMME) como un enfoque integrador para los datos longitudinales intensivos (ILD).
  • Introducir el algoritmo, las extensiones y las aplicaciones de GIMME en psicología clínica.
  • Para discutir las limitaciones de GIMME y las futuras direcciones de investigación.

Principales métodos:

  • Revisión de la estimación del modelo múltiple iterativo de grupo (GIMME).
  • Examen del algoritmo central de GIMME y las extensiones para el modelado de ILD.
  • Análisis de estudios de simulación y aplicaciones empíricas en psicología clínica.

Principales resultados:

  • GIMME estima la dinámica específica de cada persona mediante el uso de caminos compartidos por la mayoría.
  • Los estudios de simulación y las aplicaciones empíricas demuestran la utilidad de GIMME.
  • Se discuten métodos alternativos de ILD junto con el desempeño de GIMME.

Conclusiones:

  • GIMME ofrece un marco sólido para modelar dinámicas psicológicas heterogéneas en DII.
  • Se necesita un mayor refinamiento de GIMME para abordar las limitaciones actuales.
  • GIMME promueve la integración de enfoques idiográficos y nomotéticos en la investigación clínica.