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Neovascularización macular bilateral secundaria a la sepsis por una infección por derivación
Takuya Shunto1, Chikako Hara1, Tatsuto Inoue2
1Department of Ophthalmology, Osaka University Graduate School of Medicine. Suita, Japan.
Retinal cases & brief reports
|February 10, 2026
Resumen
La sepsis de las infecciones de derivación puede causar neovascularización macular bilateral (MNV) sin endocarditis infecciosa. El diagnóstico temprano y el tratamiento con inyecciones de aflibercept intravítreo pueden mejorar los resultados para esta rara complicación.
Área de la Ciencia:
- Oftalmología Oftalmología.
- Enfermedad Infecciosa Enfermedad Infecciosa.
- La neovascularización es la neovascularización.
Sus antecedentes:
- La sepsis puede conducir a complicaciones graves, incluidas las manifestaciones oculares.
- Los embolias sépticas son una causa conocida de daño en los órganos finales.
- La neovascularización macular (MNV) se asocia típicamente con la degeneración macular relacionada con la edad u otras afecciones.
Objetivo del estudio:
- Para reportar un raro caso de neovascularización macular bilateral (MNV) secundaria a una embolia séptica por una infección por derivación.
- Para resaltar la importancia de considerar el MNV en pacientes con sepsis sin endocarditis infecciosa.
Principales métodos:
- Informe de caso de observación.
- Evaluación oftalmológica que incluye tomografía de coherencia óptica (OCT) y angiografía OCT.
- Tratamiento con inyecciones de aflibercept por vía intravítrea.
Principales resultados:
- Una mujer de 57 años en hemodiálisis desarrolló MNV bilateral tipo 2 después de la sepsis de una infección por derivación.
- La agudeza visual fue de 20/25 en el ojo derecho y 20/20 en el ojo izquierdo en la presentación.
- Las inyecciones intravítreas de aflibercept redujeron la actividad de MNV y mejoraron los síntomas sin recurrencia durante un año.
Conclusiones:
- La MNV bilateral puede ocurrir secundaria a la sepsis relacionada con la infección por derivación, incluso sin endocarditis infecciosa.
- Los oftalmólogos deben considerar la MNV como una posible complicación de la sepsis de varias fuentes, no solo la endocarditis infecciosa.
- El diagnóstico y el tratamiento rápidos son cruciales para el manejo de esta condición que amenaza la vista.
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