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Síndrome recurrente de Miller Fisher: un informe de caso
Larry Vernier1, Griffin Barnes Gilmore2, Kelsey Van Housen3
1Montefiore Einstein, Department of Emergency Medicine, The Bronx, New York.
Clinical practice and cases in emergency medicine
|February 10, 2026
Resumen
Puede ocurrir el síndrome recurrente de Miller Fisher, una variante del síndrome de Guillain-Barré, que se presenta con ataxia y oftalmoplegia. El diagnóstico oportuno y el tratamiento con inmunoglobulina intravenosa son cruciales para la recuperación.
Área de la Ciencia:
- Neurología Neurología.
- Inmunología Inmunología.
Sus antecedentes:
- El síndrome de Guillain-Barré (GBS) puede causar parálisis progresiva, que a menudo requiere cuidados intensivos.
- Las recaídas de GBS se consideran raras en la práctica clínica.
Objetivo del estudio:
- Para reportar un caso de síndrome recurrente de Miller Fisher (SFM), una variante del SGB.
- Para resaltar la posibilidad de recurrencia de MFS a pesar de que la literatura sugiere lo contrario.
Principales métodos:
- Informe de caso de un hombre de 67 años con antecedentes de MFS.
- La presentación clínica incluyó ataxia, oftalmoplegia, disfonía y disfunción de la marcha.
- La evaluación diagnóstica incluyó punción lumbar que reveló una disociación albuminocitológica.
Principales resultados:
- El paciente fue diagnosticado con MFS recurrente después del inicio de los síntomas.
- El tratamiento con inmunoglobulina intravenosa (IVIG) condujo a una marcada mejora de los síntomas.
- Los déficits residuales incluyeron oftalmoplegia y disfonía leve, que requirieron rehabilitación de pacientes hospitalizados.
Conclusiones:
- El síndrome de Miller Fisher es una variante poco común de GBS con hallazgos neurológicos distintos.
- MFS requiere un alto índice de sospecha para el diagnóstico y el manejo.
- Este caso demuestra que el MFS puede reaparecer en pacientes, desafiando suposiciones anteriores.
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