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Un informe de caso de leucemia linfoblástica aguda que se presenta como dolor bilateral en la rodilla en un corredor
Michael Rosselli1, Alejandro Sanoja2, Matthew Apicella1
1Mount Sinai Medical Center, Department of Emergency Medicine, Miami Beach, Florida.
Clinical practice and cases in emergency medicine
|February 10, 2026
Resumen
La leucemia linfoblástica aguda (LLA) puede ocurrir en adultos, presentándose con síntomas no específicos como dolor de rodilla. El diagnóstico precoz es vital, ya que este caso pone de relieve el potencial de progresión rápida y resultados fatales, incluso en individuos jóvenes y sanos.
Área de la Ciencia:
- Hematología Hematología.
- Oncología Oncología.
- Medicina interna es la medicina interna de las enfermedades.
Sus antecedentes:
- La leucemia linfoblástica aguda (LLA) es predominantemente una neoplasia maligna pediátrica, pero rara vez puede afectar a los adultos.
- Los síntomas no específicos de la ALL pueden retrasar el diagnóstico, aumentando la morbilidad y la mortalidad.
- La detección temprana de la LLA en adultos es fundamental para una intervención oportuna y mejores resultados.
Objetivo del estudio:
- Para informar de un caso raro de LLA adulta que se presenta de manera atípica.
- Para resaltar los desafíos de diagnóstico asociados con la presentación de síntomas no específicos.
- Para enfatizar la importancia de la vigilancia clínica en el diagnóstico de la LLA en adultos.
Principales métodos:
- Presentación del caso de un hombre de 34 años con dolor bilateral en la rodilla.
- El análisis de diagnóstico reveló leucemia linfoblástica aguda.
- Curso clínico que detalla el síndrome de lisis tumoral y la progresión rápida.
Principales resultados:
- El paciente fue diagnosticado con LLA a pesar de presentar síntomas comunes de dolor de rodilla.
- Se desarrolló el síndrome de lisis tumoral, lo que condujo a un resultado rápido y fatal.
- El caso subraya el potencial de la ALL para imitar condiciones benignas.
Conclusiones:
- El dolor en las articulaciones, incluido el dolor de rodilla, puede ser un síntoma inicial de la LLA en adultos.
- La artritis leucémica es una presentación reconocida, aunque poco común, de la ALL.
- Los médicos deben mantener un alto índice de sospecha de LLA en pacientes con síntomas persistentes o inexplicables, evitando sesgos cognitivos.
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