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La deriva del sistema de desarrollo en el patrón del tarso de artrópodos
Benjamin Klementz1, Sophie Neu1, Ethan Laumer1
1Department of Integrative Biology, University of Wisconsin-Madison, Madison, WI53706, USA.
Proceedings. Biological sciences
|February 10, 2026
Resumen
La eliminación del gen sin garras de Harvestman interrumpe el desarrollo del tarso, a diferencia de los insectos donde especifica la garra. Esto sugiere un cambio en la función génica durante la evolución de las patas de los artrópodos.
Área de la Ciencia:
- Biología del desarrollo Biología del desarrollo.
- Biología evolutiva Biología evolutiva.
- Genética La genética.
Sus antecedentes:
- El patrón del eje proximodistal en las patas de los artrópodos se estudia principalmente en insectos.
- Se hipotetiza una red reguladora de genes conservada para el patrón de las piernas en todos los artrópodos.
- Los chelicerados muestran patrones de apéndices divergentes, con datos funcionales limitados.
Objetivo del estudio:
- Para investigar la función del gen sin garras en el cosechador Phalangium opilio.
- Para comparar la función del gen sin garras entre insectos y chelicerates.
- Para inferir la función ancestral de las garras en Chelicerata.
Principales métodos:
- La interferencia del ARN (RNAi) para derribar la expresión sin garras en el Phalangium opilio.
- Análisis del crecimiento tarsal, el patrón y la formación de tarsómero después de la caída.
- Encuestas de expresión de homólogos sin garras a través de diversos chelicerados.
Principales resultados:
- La caída sin garras en los cosechadores interrumpió el crecimiento tarsal y el patrón de límite proximal.
- No se observó ningún efecto en la formación de garras en los experimentos de knockdown.
- Los patrones de expresión sugieren un papel conservado de patrones de tarso para los sin garras en Chelicerata.
Conclusiones:
- Harvestman sin garras tiene una función distinta en el patrón tarsal en comparación con los insectos sin garras.
- La función ancestral de los sin garras en Chelicerata probablemente involucró el patrón tarsal.
- La deriva del sistema de desarrollo contribuye a la diversidad de patrones de apéndice de panartrópodos.
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