El análisis pan-genómico revela la dinámica evolutiva y la divergencia funcional de la familia de genes de la O-metiltransferasa en el tomate

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Haibin Wang^1,2, Xumin Ou^1,2, Jianing Zhang^1,2

¹State Key Laboratory of Tropical Crop Breeding, School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya, 572025, China.

Journal of integrative plant biology

|February 10, 2026

Resumen

Este estudio revela la historia evolutiva de los genes de la O-metiltransferasa (OMT) en las plantas, identificando genes clave involucrados en la defensa y adaptación de las plantas. Destaca la divergencia funcional dentro de la subfamilia CCoAOMT, crucial para comprender el metabolismo de las plantas.

Área de la Ciencia:

Biología molecular vegetal Biología molecular vegetal
La genómica evolutiva es una genómica evolutiva.
La bioquímica es la bioquímica.

Sus antecedentes:

Las O-metiltransferasas (OMTs) son vitales para la defensa y el metabolismo de las plantas.
Comprender la evolución de la familia de genes OMT y la divergencia funcional es crucial.

Objetivo del estudio:

Para analizar la trayectoria evolutiva de la familia de genes OMT a través de las especies de plantas.
Para aclarar la divergencia funcional de la subfamilia CCoAOMT.
Para identificar genes involucrados en la biosíntesis de flavonoides metilados isoméricos en el tomate.

Principales métodos:

Análisis pan-genómico de los genes OMT en 61 accesos de tomate.
Análisis filogenético de genes OMT en 20 especies de plantas.
Espectrometría de movilidad iónica para el análisis de la actividad enzimática.

Principales resultados:

Se identificaron 2.882 genes OMT en 20 especies de plantas, con 2.199 en el tomate.
El análisis filogenético trazó la evolución de CCoAOMT hasta un solo linaje ancestral.
Descubrió el papel específico de SlCOMT2c en la biosíntesis de kaempferida y la nueva metilación de luteolina de SlAOMT.

Conclusiones:

Estableció un marco evolutivo para la familia de genes OMT de plantas.
Se identificaron genes clave y redes reguladoras en la biosíntesis de flavonoides metilados.
Proporcionó herramientas para estudiar la evolución adaptativa de las plantas y el metabolismo especializado.

Palabras clave:

Las O-metiltransferasas.historia evolutiva de la historia de la evolución.Caracterización de las características funcionales.familia pan-genética de la familia.El tomate el tomate el tomate el tomate el tomate el tomate.

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