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El consumo materno de nano jengibre: implicaciones para el desarrollo fetal y la organogénesis en modelos de ratas
Zahida M H AlQayyim1, Zahraa H Al-Qaim2, Ammar F J Al-Tu'ma3
1Department of Pathological Analysis, College of Science, University of Al-Qadissiyah, Al-Qadissiyah, Iraq.
Advanced biomedical research
|February 11, 2026
Resumen
La administración de nano jengibre durante el embarazo no causó efectos teratogénicos o toxicidad en fetos de ratas. Este estudio confirma que el nano jengibre es seguro para la organogénesis fetal, incluso en dosis altas.
Área de la Ciencia:
- Farmacología Farmacología.
- Toxicología del desarrollo.
- La nanomedicina es la nanomedicina.
Sus antecedentes:
- Las propiedades farmacológicas del jengibre plantean preocupaciones sobre los posibles efectos teratogénicos durante el embarazo.
- La organogénesis es un período crítico para el desarrollo fetal, sensible a las influencias externas.
Objetivo del estudio:
- Para evaluar los efectos del nano jengibre en la organogénesis fetal en ratas embarazadas.
- Evaluar la seguridad y la potencial teratogenicidad del nano jengibre durante el embarazo.
Principales métodos:
- 230 ratas embarazadas fueron divididas en tres grupos que recibieron diferentes dosis de nano jengibre (50, 500, 1000 mg/kg).
- El monitoreo incluyó el peso corporal, la ingesta de alimentos y el consumo de agua.
- El examen fetal en el día 21 de la gestación evaluó la teratogenicidad y la toxicidad.
Principales resultados:
- No se observaron muertes ni resultados adversos en los grupos de tratamiento.
- El nano jengibre no afectó el rendimiento reproductivo.
- No se encontraron signos de embriotoxicidad o teratogenicidad en el desarrollo fetal.
Conclusiones:
- La administración de nano jengibre durante la organogénesis en ratas no es tóxica para la madre y no daña el desarrollo embrionario o fetal.
- Los hallazgos indican seguridad para la organogénesis fetal en las dosis diarias probadas hasta 1000 mg/kg.
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