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Cribado cognitivo basado en realidad virtual en psiquiatría: Investigando los límites óptimos para el deterioro
Andreas Elleby Jespersen1,2, Julie Marie Lindhardsen2, Anders Lumbye3
1Neurocognition and Emotion Across Disorders of the Brain (NEAD) Centre, Psychiatric Centre Copenhagen, Frederiksberg Hospital, Copenhagen, Denmark.
Neuroscience applied
|February 11, 2026
Resumen
La realidad virtual (RV) ofrece una nueva forma de evaluar el deterioro cognitivo en el trastorno bipolar (TB). La prueba Cognition Assessment in Virtual Reality (CAVIR) se muestra prometedora como una herramienta de detección ecológicamente válida para los desafíos cognitivos del mundo real.
Área de la Ciencia:
- La neurociencia es la neurociencia.
- La psiquiatría es la psiquiatría.
- Interacción hombre-computadora Interacción hombre-computadora.
Sus antecedentes:
- El deterioro cognitivo es un problema significativo en los trastornos neuropsiquiátricos como el trastorno bipolar (TB).
- Las pruebas neuropsicológicas tradicionales pueden no reflejar con precisión las dificultades cognitivas del mundo real.
- La realidad virtual (VR) presenta una oportunidad para evaluaciones cognitivas más ecológicamente válidas.
Objetivo del estudio:
- Para determinar la puntuación óptima de corte para la evaluación de la cognición en la realidad virtual (CAVIR).
- Evaluar la efectividad de CAVIR en la identificación de la capacidad cognitiva funcional deteriorada en pacientes con BD.
- Para validar el rendimiento de CAVIR en una población de pacientes más amplia.
Principales métodos:
- Los análisis de las características operativas del receptor (ROC) se utilizaron para identificar las puntuaciones óptimas de corte.
- El estudio involucró a pacientes ambulatorios con BD y una muestra mixta de pacientes con trastornos del espectro del estado de ánimo o esquizofrenia.
- La pantalla para el deterioro cognitivo en psiquiatría (SCIP) y una batería neuropsicológica completa sirvieron como estándares de referencia.
Principales resultados:
- Un punto de corte de la puntuación total de CAVIR de ≤64 demostró una sensibilidad del 74% y una especificidad del 71% en la muestra primaria de BD (AUC = 0,74).
- Se identificó una puntuación robusta de corte de ≤66 en la muestra de replicación.
- El rendimiento de CAVIR mostró asociaciones moderadas con medidas cognitivas objetivas y resultados funcionales.
Conclusiones:
- La prueba CAVIR exhibe una sensibilidad y especificidad razonables para detectar deterioro cognitivo.
- CAVIR muestra potencial como una herramienta de detección ecológicamente válida para la capacidad cognitiva funcional.
- Esta evaluación basada en realidad virtual podría mejorar la identificación de los desafíos cognitivos en los trastornos neuropsiquiátricos.
Palabras clave:
El trastorno bipolar es un trastorno bipolar.La cognición es la cognición.Deterioro cognitivo El deterioro cognitivo es un deterioro cognitivo.Las pruebas de detección cognitiva.Validez ecológica La validez ecológica.Trastornos del estado de ánimo trastornos del estado de ánimoLa realidad virtual es la realidad virtual.
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