Video Experimental Relacionado

Updated: Feb 12, 2026

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

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Enfoque de RMN sin Marcar con Asignaciones de Metilo Específicas del Sitio para la Evaluación Estructural de la

Saeko Yanaka1,2,3,4,5, Yuuki Koseki4,5, Yohei Miyanoiri1,3,6

  • 1Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural Sciences, 5-1 Myodaiji, Okazaki, Aichi 444-8787, Japan.

Journal of the American Chemical Society
|February 11, 2026
PubMed
Resumen

La espectroscopía de resonancia magnética nuclear (RMN) ahora ofrece información a nivel de residuo sobre la estructura de orden superior (HOS) de los anticuerpos terapéuticos. Este enfoque de RMN de metilo sin marcar permite la evaluación sensible de la glicosilación y las modificaciones para el control de calidad.

Palabras clave:
RMN de metilo sin marcarestructura de orden superioranticuerpos terapéuticoscontrol de calidadIgG1 Fc

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