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Plasma de color café: ¿Qué interferencia debe considerarse?
Clinical laboratory
|February 11, 2026
Resumen
Este estudio destaca una inusual coloración de plasma marrón que causó discrepancias en las mediciones de bilirrubina. Los datos exactos de la fase preanalítica y analítica son cruciales para evitar resultados incorrectos en pacientes debido a interferencias.
Área de la Ciencia:
- Química clínica es la química clínica.
- La bioquímica analítica es la bioquímica analítica.
- Medicina de laboratorio y medicina de laboratorio.
Sus antecedentes:
- La apariencia icterica o lipémica del suero es común en la práctica clínica.
- Los índices de hemólisis, icterus y lipemia (HIL) se pueden determinar por espectrofotometría.
- Las interferencias endógenas como HIL pueden afectar la precisión de los resultados de las pruebas de laboratorio.
Objetivo del estudio:
- Para reportar un caso atípico de coloración de plasma marrón.
- Para investigar las discrepancias entre la bilirrubina medida y el índice icterus.
- Para enfatizar la importancia de los datos de la fase preanalítica y analítica.
Principales métodos:
- Observación visual de la coloración del plasma.
- Determinación espectrofotométrica de los índices HIL.
- Análisis de las discrepancias en un entorno de laboratorio clínico.
Principales resultados:
- Se observó una atípica coloración de plasma marrón, "como el café".
- Esta coloración inusual condujo a una discrepancia entre la bilirrubina total y el índice icterus.
- La interferencia observada afectó el análisis de laboratorio de rutina.
Conclusiones:
- Es vital preservar la información de la fase preanalítica y analítica.
- Las interferencias analíticas pueden conducir a resultados incorrectos o indebidamente cancelados.
- Es necesaria una evaluación cuidadosa de la apariencia de la muestra y los datos analíticos para garantizar la precisión de los resultados.
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