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Efecto de la terapia de activación del barorreflejo en las mediciones de la presión arterial en el hogar después de
Leon Ernst1, Manuel Wallbach2,3, Wilhelm Zander1
1University of Cologne, Faculty of Medicine and University Hospital Cologne, Clinic III for Internal Medicine, Cologne.
Journal of hypertension
|February 11, 2026
Resumen
La terapia de activación del barorreflejo (BAT) ofrece una reducción de la presión arterial a largo plazo en la hipertensión resistente. La desactivación del dispositivo aumentó temporalmente la presión arterial en el hogar, lo que confirma las MTD.
Área de la Ciencia:
- Cardiología Cardiología.
- Gestión de la gestión de la hipertensión.
- Dispositivos Médicos Dispositivos Médicos para el Cuerpo
Sus antecedentes:
- La terapia de activación del barorreflejo (BAT) es un tratamiento para la hipertensión resistente.
- Los datos de eficacia a largo plazo de ensayos aleatorizados son limitados.
Objetivo del estudio:
- Para investigar el impacto a largo plazo de la desactivación y reactivación de la terapia de activación de barorreflejo (BAT) en la presión arterial.
- Evaluar el efecto sostenido de las MTD en pacientes con hipertensión resistente.
Principales métodos:
- Un estudio prospectivo, aleatorizado y de dos centros en el que participaron pacientes con hipertensión resistente sometidos a reemplazo de dispositivos BAT.
- Los pacientes fueron asignados al azar en dos grupos con períodos escalonados de desactivación y reactivación.
- La presión arterial (BP) en la oficina y en el hogar fue monitoreada por médicos a ciegas y mediciones telemétricas.
Principales resultados:
- Se incluyeron dieciséis pacientes con una mediana de 50 meses de tratamiento con MTD.
- La desactivación del dispositivo BAT aumentó significativamente la presión arterial en el hogar en 5 ± 7 mmHg (P < 0,05).
- La presión arterial de la oficina aumentó en 8 ± 14 mmHg después de 4 semanas de desactivación (P = 0,06).
Conclusiones:
- La desactivación temporal de las MTD conduce a un aumento significativo de la presión arterial en el hogar.
- Esto sugiere un efecto de disminución de la presión arterial moderado y sostenido de la MTD incluso después de una terapia a largo plazo.
- La MTD sigue siendo una opción viable para el manejo de la hipertensión resistente.
Palabras clave:
Las MTD son las MTD más bajas.Se trata de BP BP BP.El IQR es el IQR.El barorreflejo es un reflejo barorreflejo.Terapia de activación del barorreflejo con terapia de activación del barorreflejoPresión arterial presión arterial presión arterialel riesgo cardiovascular.el diseño de los cruces.El rango intercuartílico es el rango intercuartílico.El estudio prospectivo es un estudio prospectivo.La aleatorización de la asignación al azar.La hipertensión resistente es resistente.
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