Video Experimental Relacionado
Updated: Feb 13, 2026
05:00
Grade III Varicocele Surgical Treatment using Spermatic Vein-Superficial Abdominal Vein Shunt
Published on: August 23, 2024
2.8K
La esteroidogénesis en los niños tiene restos suprarrenales en el cordón espermático
Tsubasa Shironomae1, Yuto Yamazaki2, Shinako Takeda3
1Department of Urology, Miyagi Children's Hospital, Sendai, Japan; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Japan.
The Journal of surgical research
|February 11, 2026
Resumen
Los descansos suprarrenales pediátricos en el cordón espermático muestran esteroideogénesis normal, con corteza suprarrenal fetal presente en la infancia y disminuyendo con la edad. La biosíntesis de la aldosterona puede diferir de las glándulas suprarrenales eutópicas.
Área de la Ciencia:
- Endocrinología Pediátrica Endocrinología pediátrica.
- Patología Quirúrgica Patología Quirúrgica.
- La esteroideogénesis es la esteroideogénesis.
Sus antecedentes:
- Los restos suprarrenales son tejidos suprarrenales ectópicos que se encuentran en el cordón espermático.
- La evaluación de la esteroideogénesis en estos restos es crucial para comprender la función adrenal pediátrica.
Objetivo del estudio:
- Para investigar la esteroideogénesis y los efectos de los andrógenos en los niños, la glándula suprarrenal descansa dentro del cordón espermático.
Principales métodos:
- Revisión retrospectiva de las exploraciones quirúrgicas pediátricas para las masas de cordón espermático.
- Análisis inmunohistoquímico de las enzimas esteroideogénicas, el receptor de andrógenos y Ki-67 en restos suprarrenales resecados.
Principales resultados:
- Se identificaron diez recesos suprarrenales en nueve pacientes pediátricos.
- Los descansos suprarrenales mostraron múltiples zonas corticales, con corteza fetal presente en la infancia, disminuyendo con la edad.
- Se detectó inmunoreactividad para las enzimas esteroideogénicas clave (CYP11B2, P450 17A1) y el receptor de andrógenos, que varía según la edad y la zona.
- Los marcadores de proliferación de Ki-67 estaban principalmente en la infancia.
Conclusiones:
- La esteroidogénesis en los descansos suprarrenales del cordón espermático se considera normal, aunque la biosíntesis de aldosterona puede diferir de las glándulas suprarrenales eutópicas.
- Los cambios relacionados con la edad en los descansos suprarrenales incluyen la presencia de corteza fetal y una expresión enzimática variable.
Videos de Conceptos Relacionados
01:21The Resting Membrane Potential
143.3K
Overview
143.3K
01:24Resting Membrane Potential
22.1K
The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
22.1K
01:17Anatomy of the Adrenal Glands
4.9K
The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
4.9K
01:27Adrenal Gland Disorders
3.3K
Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
3.3K
01:15Resting Potential Decay
6.5K
The resting membrane potential of a neuron (-70mV) is sustained due to the selective ion permeability of the membrane. At the resting potential, the membrane is slightly permeable to ions like sodium (Na+) and chloride (Cl−) and highly permeable to potassium ions (K+). Differences in the ions' concentration inside the cell compared to the outside are maintained by membrane transport proteins like channels and pumps.
At rest, the K+ is the main ion that moves across the membrane...
At rest, the K+ is the main ion that moves across the membrane...
6.5K
01:31Hormones of the Adrenal Glands
5.5K
Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
5.5K