Video Experimental Relacionado

Updated: Feb 13, 2026

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions
10:27

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

Published on: October 21, 2022

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Análisis en silicio del modo de unión de la verteporfina, un inhibidor de la interacción YAP-TEAD

Yurika Ikegami1, Genki Kudo2, Takumi Hirao3

  • 1Degree Programs in Comprehensive Human Sciences, Graduate School of Comprehensive Human Sciences, Doctoral Program in Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki 305-8575, Japan.

Chemical & pharmaceutical bulletin
|February 11, 2026
PubMed
Resumen

Los isómeros de verteporfina fueron analizados para su unión a YAP-TEAD. El isómero Ia-2 muestra el modo de unión inhibidora más prometedor, lo que sugiere un potencial para mejorar la terapia contra el cáncer al aislar este isómero específico.

Palabras clave:
El modelado de AlphaFold2 en el modelo AlphaFold2.Proteína asociada a sí Interacción del dominio TEA.Acoplamiento molecular de acoplamiento molecular.Proteinligand interacción huella dactilar huella dactilarEl isómero de la verteporfina es el verteporfin.

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