Video Experimental Relacionado
Updated: Feb 13, 2026
09:12
Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
Published on: January 12, 2018
15.5K
La proliferación bacteriana es comparable en los concentrados de glóbulos rojos almacenados en contenedores
Sandra Ramirez-Arcos1,2, Yuntong Kou1, Dilini Kumaran1
1Product & Process Development, Canadian Blood Services, Ottawa, Ontario, Canada.
Vox sanguinis
|February 11, 2026
Resumen
Los concentrados de glóbulos rojos (RBCC) almacenados en bolsas DEHT/PAGGSM mostraron un crecimiento bacteriano similar al de las bolsas DEHP/SAGM. Esto indica que los contenedores libres de DEHP no aumentan los riesgos de seguridad bacteriana para el almacenamiento de RBCC.
Área de la Ciencia:
- Ciencias biomédicas Ciencias biomédicas.
- Medicina para la transfusión de sangre.
- Ciencia de los materiales ciencia de los materiales.
Sus antecedentes:
- La UE está prohibiendo el di2-etilhexil) ftalato (DEHP) en los dispositivos médicos para el año 2030.
- El DEHP es un plastificante en las bolsas de sangre de cloruro de polivinilo (PVC), crucial para el almacenamiento del concentrado de glóbulos rojos (RBCC).
- Se están explorando alternativas libres de DEHP como el di ((2-etilhexil) tereftalato (DEHT).
Objetivo del estudio:
- Para comparar el crecimiento bacteriano en los RBCC almacenados en contenedores DEHT/PAGGSM frente a los contenedores DEHP/SAGM.
- Para evaluar la seguridad bacteriana de las soluciones de almacenamiento de RBCC libres de DEHP.
Principales métodos:
- Se prepararon RBCC y se dividieron en dos condiciones de almacenamiento: DEHT/PAGGSM y DEHP/SAGM.
- Las bolsas fueron inoculadas con bacterias específicas (Yersinia enterocolitica, Serratia liquefaciens, Listeria monocytogenes, Cutibacterium acnes).
- Los recuentos bacterianos fueron monitoreados durante 43 días a 1-6°C.
Principales resultados:
- No se observó ninguna diferencia significativa en el crecimiento bacteriano para Y. enterocolitica, S. liquefaciens y C. acnes entre las dos condiciones de almacenamiento.
- L. monocytogenes mostró recuentos transitoriamente más bajos en bolsas DEHT/PAGGSM inicialmente, pero alcanzó niveles similares al día 43.
- Las cargas bacterianas alcanzaron niveles altos (10-109 CFU/mL) para algunas especies al día 14.
Conclusiones:
- Los RBCC almacenados en contenedores DEHT/PAGGSM no presentan un mayor riesgo de seguridad bacteriana en comparación con los de las bolsas DEHP/SAGM.
- Las soluciones de almacenamiento de RBCC sin DEHP parecen seguras con respecto a la contaminación bacteriana.
Videos de Conceptos Relacionados
02:41Concentration Cells
25.9K
A concentration cell is a type of a voltaic cell constructed by connecting two almost identical half-cells, both based on the same half-reaction and using the same electrode, differing only in the concentration of one redox species. A concentration cell's potential, therefore, is determined only by the concentration difference of the particular redox species.
Consider the following voltaic cell:
Consider the following voltaic cell:
25.9K
01:12Energy Stored in a Capacitor
4.8K
When an archer pulls the string in a bow, he saves the work done in the form of elastic potential energy. When he releases the string, the potential energy is released as kinetic energy of the arrow. A capacitor works on the same principle in which the work done is saved as electric potential energy. The potential energy (UC) could be calculated by measuring the work done (W) to charge the capacitor.
4.8K
02:36Cells Coordinate Growth and Proliferation
5.1K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
5.1K
01:10Energy Stored in Capacitors
1.1K
A parallel plate capacitor, when connected to a battery, develops a potential difference across its plates. This potential difference is key to the operation of the capacitor, as it determines how much electrical energy the capacitor can store.
By integrating the equation that relates voltage and current in a capacitor, one can derive an equation for the voltage across the capacitor at any given time. This equation is crucial in understanding and predicting the behavior of capacitors in...
By integrating the equation that relates voltage and current in a capacitor, one can derive an equation for the voltage across the capacitor at any given time. This equation is crucial in understanding and predicting the behavior of capacitors in...
1.1K
01:16Energy Stored in Inductors
964
An inductor is ingeniously crafted to accumulate energy within its magnetic field. This field is a direct result of the current that meanders through its coiled structure. When this current maintains a steady state, there is no detectable voltage across the inductor, prompting it to mimic the behavior of a short circuit when faced with direct current.
In terms of gauging the energy stored within an inductor, it is equivalent to the integral of the power delivered at every individual moment, all...
In terms of gauging the energy stored within an inductor, it is equivalent to the integral of the power delivered at every individual moment, all...
964
01:26Energy Stored in a Capacitor: Problem Solving
1.8K
In 1749, Benjamin Franklin coined the word battery for a series of capacitors connected to store energy. Capacitors store electric potential energy that can be released over a short time. This property means capacitors have a wide range of applications.
Capacitor-discharge ignition is a type of ignition system commonly found in small engines where the energy released from a capacitor ignites an induction coil that, in turn, fires the spark plug.
To calculate the energy stored in a capacitor of...
Capacitor-discharge ignition is a type of ignition system commonly found in small engines where the energy released from a capacitor ignites an induction coil that, in turn, fires the spark plug.
To calculate the energy stored in a capacitor of...
1.8K