Prevalencia de fragilidad preoperatoria y factores de riesgo en pacientes con cáncer oral: un metanálisis
Video Experimental Relacionado
Updated: Feb 13, 2026
05:53
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
Published on: July 24, 2013
17.1K
Huipin Wang1, Jianhuan Che2, Ye Zhang2
1School of Nursing, Jilin University, No.965 Xinjiang Street, Changchun 130021, Jilin, China.
The British journal of oral & maxillofacial surgery
|February 11, 2026
Resumen
La prevalencia de la fragilidad preoperatoria en pacientes con cáncer oral es del 42,2%. Los principales factores de riesgo incluyen la edad avanzada y las comorbilidades, mientras que el índice de masa corporal ofrece protección, guiando las intervenciones clínicas.
Área de la Ciencia:
- Medicina Geriátrica La medicina geriátrica es una especialidad de la medicina geriátrica.
- Oncología Oncología.
- Investigación quirúrgica en la investigación quirúrgica.
Sus antecedentes:
- La fragilidad preoperatoria es una preocupación significativa en pacientes con cáncer oral.
- La identificación de la prevalencia de la fragilidad y los factores de riesgo es crucial para optimizar los resultados de los pacientes.
Objetivo del estudio:
- Para determinar la prevalencia de la fragilidad preoperatoria en pacientes con cáncer oral.
- Para identificar los factores de riesgo asociados con la fragilidad preoperatoria en esta población.
Principales métodos:
- Una revisión sistemática y un metanálisis de los estudios observacionales publicados hasta el 30 de agosto de 2025.
- La inclusión de 18 artículos, con riesgo de sesgo y calidad evaluada utilizando criterios NOS y AHRQ.
Principales resultados:
- La prevalencia de la fragilidad preoperatoria entre los pacientes con cáncer oral fue del 42,2%.
- Los factores de riesgo identificados incluyen edad avanzada, deterioro cognitivo, puntuación ASA ≥3, polifarmacia (>5 medicamentos), puntuación CCI ≥2 y IMC bajo.
- Un IMC más alto fue identificado como un factor protector contra la fragilidad.
Conclusiones:
- Una proporción sustancial de pacientes con cáncer oral presentan fragilidad preoperatoria.
- La comprensión de estos factores de riesgo permite intervenciones específicas para mitigar el impacto de la fragilidad.
- Los hallazgos apoyan el desarrollo de estrategias para prevenir, revertir o retrasar la progresión de la fragilidad en la atención del cáncer oral.
Videos de Conceptos Relacionados
01:26Factors Affecting the Risk of Infection
13.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.8K
01:24Drug Toxicity: Risk factors
1
Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
1
01:08Prevalence and Incidence
1.9K
In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K
01:29Factors Affecting Protein-Drug Binding: Patient-Related Factors
338
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
338
01:21Cancer Survival Analysis
774
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
774
01:09Directing Effect of Substituents: meta-Directing Groups
6.0K
Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.0K