Jove
Visualize
Contáctanos
JoVE
x logofacebook logolinkedin logoyoutube logo
ACERCA DE JoVE
Visión GeneralLiderazgoBlogCentro de Ayuda JoVE
AUTORES
Proceso de PublicaciónConsejo EditorialAlcance y PolíticasRevisión por ParesPreguntas FrecuentesEnviar
BIBLIOTECARIOS
TestimoniosSuscripcionesAccesoRecursosConsejo Asesor de BibliotecasPreguntas Frecuentes
INVESTIGACIÓN
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchivo
EDUCACIÓN
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualCentro de Recursos para ProfesoresSitio de Profesores
Términos y Condiciones de Uso
Política de Privacidad
Políticas

Videos de Conceptos Relacionados

Transdermal Drug Delivery Systems01:18

Transdermal Drug Delivery Systems

3
Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...
3
Ophthalmic Drug Delivery Systems01:23

Ophthalmic Drug Delivery Systems

1
Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...
1
Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

1
Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
1
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

1
Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
1
Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

1
Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
1
Oral Drug Delivery Systems: Delayed-Release Systems01:11

Oral Drug Delivery Systems: Delayed-Release Systems

2
Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...
2

También podría leer

Artículos Relacionados

Artículos vinculados a este trabajo por autores compartidos, revista y gráfico de citas.

Ordenar por
Same author

A Heat-Inactivated Two-Strain <i>Lacticaseibacillus paracasei</i> Fermented Milk as a Postbiotic for Functional Constipation: A Randomized, Double-Blind, Placebo-Controlled Trial.

Nutrients·2026
Same author

Isomeric Dibenzodiindenophenanthrene Diradicaloids: Synthesis, Structures, Properties, and Efficient NIR Photothermal Conversion for Imaging.

Angewandte Chemie (International ed. in English)·2026
Same author

Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same author

Long-term outcomes of one-stop unilateral thoracoscopic hybrid ablation for persistent atrial fibrillation after failed catheter ablation.

Journal of cardiothoracic surgery·2026
Same author

The KIF6-RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Psychosocial pathways linking type D personality traits to quality of life in patients with permanent intestinal stomas: a cross-sectional structural equation modeling study.

Frontiers in medicine·2026

Video Experimental Relacionado

Updated: Feb 13, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

16.0K

Avances recientes en sistemas de administración de probióticos basados en nanofibras

Xuemin Qin1, Mengmei Xu1, Hanglian Lan2

  • 1Key Laboratory of Geriatric Nutrition and Health (Beijing Technology and Business University), Ministry of Education, Beijing Technology and Business University (BTBU), Beijing, China.

Critical reviews in food science and nutrition
|February 12, 2026
PubMed
Resumen

Las nanofibras ofrecen una solución novedosa para la administración de probióticos, protegiendo a estos microbios beneficiosos de las duras condiciones gastrointestinales. Esta revisión explora cómo la encapsulación en nanofibras mejora la viabilidad y función de los probióticos.

Palabras clave:
Liberación controladaestabilidad gastrointestinalnanofibraprebióticoprobiótico

Más Videos Relacionados

Author Spotlight: Unlocking Plant Transformation by Innovating with Carbon Nanofiber Arrays
05:32

Author Spotlight: Unlocking Plant Transformation by Innovating with Carbon Nanofiber Arrays

Published on: July 21, 2023

2.2K
Microhoneycomb Monoliths Prepared by the Unidirectional Freeze-drying of Cellulose Nanofiber Based Sols: Method and Extensions
09:20

Microhoneycomb Monoliths Prepared by the Unidirectional Freeze-drying of Cellulose Nanofiber Based Sols: Method and Extensions

Published on: May 24, 2018

9.5K

Videos de Experimentos Relacionados

Last Updated: Feb 13, 2026

Synthesis of Keratin-based Nanofiber for Biomedical Engineering
14:43

Synthesis of Keratin-based Nanofiber for Biomedical Engineering

Published on: February 7, 2016

16.0K
Author Spotlight: Unlocking Plant Transformation by Innovating with Carbon Nanofiber Arrays
05:32

Author Spotlight: Unlocking Plant Transformation by Innovating with Carbon Nanofiber Arrays

Published on: July 21, 2023

2.2K
Microhoneycomb Monoliths Prepared by the Unidirectional Freeze-drying of Cellulose Nanofiber Based Sols: Method and Extensions
09:20

Microhoneycomb Monoliths Prepared by the Unidirectional Freeze-drying of Cellulose Nanofiber Based Sols: Method and Extensions

Published on: May 24, 2018

9.5K

Área de la Ciencia:

  • Biotecnología
  • Ciencia de los materiales
  • Microbiología

Sus antecedentes:

  • Los probióticos ofrecen beneficios para la salud pero luchan con la viabilidad debido a los desafíos gastrointestinales.
  • Los métodos de administración existentes enfrentan limitaciones para proteger los probióticos.
  • Las nanofibras presentan una matriz prometedora para la encapsulación mejorada de probióticos.

Objetivo del estudio:

  • Revisar sistemáticamente los avances recientes en la encapsulación de probióticos utilizando nanofibras.
  • Analizar el uso de biopolímeros naturales, sintéticos y compuestos en la fabricación de nanofibras.
  • Discutir el papel de los prebióticos en la mejora de los sistemas de administración de probióticos.

Principales métodos:

  • Revisión de literatura centrada en la encapsulación de probióticos mediante nanofibras.
  • Análisis de diferentes materiales biopoliméricos utilizados para la construcción de la pared de nanofibras.
  • Evaluación de la viabilidad, estabilidad y funcionalidad de los probióticos dentro de las matrices de nanofibras.

Principales resultados:

  • Las nanofibras encapsulan eficazmente los probióticos, mejorando su supervivencia y eficacia.
  • Varios biopolímeros (naturales, sintéticos, compuestos) demuestran ser adecuados para la producción de nanofibras.
  • La incorporación de prebióticos potencia aún más los beneficios de las nanofibras cargadas de probióticos.

Conclusiones:

  • La encapsulación en nanofibras es una estrategia superior para mejorar la administración y función de los probióticos.
  • Se justifica una mayor investigación sobre la optimización de materiales y estudios in vivo.
  • Esta tecnología tiene un potencial significativo para alimentos funcionales y aplicaciones terapéuticas.