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Updated: Feb 13, 2026

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Propiedades estructurales y dinámicas del dominio YTH en complejo con ARN N⁶-metiladenosina estudiadas mediante

Mingwei Li1, Guanglin Chen2, Zhiyong Zhang1,2

  • 1MOE Key Laboratory for Membraneless Organelles & Cellular Dynamics National Science Center for Physical Sciences at Microscale Division of Life Sciences and Medicine, and Biomedical Sciences and Health Laboratory of Anhui Province University of Science and Technology of China Hefei 230026 China.

Quantitative biology (Beijing, China)
|February 12, 2026
PubMed
Resumen

El dominio YTH se une al ARN metilado de manera más eficaz que al ARN no metilado, revelando residuos hidrofóbicos clave involucrados en esta interacción. Este estudio mejora la comprensión de la dinámica del complejo YTH-ARN y los mecanismos de unión.

Palabras clave:
metilación del ARNARN YTH-m6A3energía libre de uniónPCA basado en contactosanálisis de componentes principales (PCA)

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