Video Experimental Relacionado
Updated: Feb 13, 2026

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
Published on: July 22, 2020
Giros y caídas en conductores de edad avanzada
Abstract:
As cognitive decline progresses, older adults may self-regulate their driving. Avoidance of left turns across traffic is observable in naturalistic driving data but rarely self-reported. We studied 106 older adults using baseline and one-year follow-up neuropsychological assessments. In-vehicle sensors passively recorded driving behavior over 12 weeks. We identified 295,112 turns from vehicle heading changes. We used mixed-effects logistic regression to model the odds of turning left, with cognitive status category change from baseline to one-year follow-up as the predictor. Greater cognitive impairment, represented by movement to a more severe cognitive status category at one-year follow-up, was associated with reduced odds of turning left (odds ratio = 0.984, 95% confidence interval = 0.969-0.999; P value = .037). Left-turn avoidance may be a behavioral marker of early cognitive decline. Passive driving data could help detect functional changes, enabling intervention to preserve mobility and independence. Further research is needed to establish a clinical threshold of concern for decreasing trends in left turn frequency in older drivers.
Videos de Conceptos Relacionados
Aging
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
The Effect of Aging on Tissues
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Pharmacodynamics in Geriatric Patients: Effects of Age
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

