Video Experimental Relacionado
Updated: Feb 13, 2026

Animal Models of Depression - Chronic Despair Model CDM
Published on: September 23, 2021
Análisis de posibles categorías de depresión en adultos mayores con enfermedades crónicas
Yiping Qu1, Xiaomin Sun1, Ya Zhao1
1The Third Hospital of Xi'an, Xi'an, Shaanxi, China.
Objective:
This study aims to explore the prevalence of depression in older adults with chronic diseases and to identify heterogeneous subgroups within this population. Additionally, we seek to investigate the influencing factors associated with depressive conditions among older adults. This study aims to provide a foundational reference for the development of targeted intervention programs.
Methods:
This study utilized data from the 2018 China Health and Aging Tracking Survey (CHARLS), including 5,878 older adults with chronic diseases. We explored potential categories of depression among these individuals through latent profile analysis. Additionally, one-way chi-square tests and one-way ANOVA were employed for single factor, while multi-factor correlation was identified via multinomial logistic regression analysis.
Results:
A total of 5,878 older adults with chronic diseases were included in this study. The participants were categorized into four groups: low level (1,904; 32.4%), low level with high despair (304; 5.2%), medium level (2,963; 50.4%), and high level (707; 12.0%). Univariate analysis of variance revealed significant differences among all variables, except for the presence of only one child. In comparison to the low level group (i.e., control group), the factors influencing the high level group included anxiety, instrumental activities of daily living (IADL), living alone, self-assessment of current life and health, exercise, activity limitation, financial self-assessment, and marital status. For the medium level group significant factors included anxiety, living alone, health self-evaluation, alcohol use, exercise, and activity limitation. Influential factors for the low level with high despair group include health self-evaluation, exercise, engagement in regular physical labor, and economic self-assessment.
Limitations:
The CES-D-10 scale may not fully capture the presence of depression in older adults with high levels of chronic illness.
Conclusion:
Depression in older adults with chronic illnesses, stemming from both physical and psychological factors, can significantly impact their overall health status. Therefore, it is essential to provide more targeted healthcare services tailored to the diverse needs of this population in future community health initiatives. Such approaches aim to improve depressive symptoms and enhance the quality of life for older adults.
Más Videos Relacionados
Videos de Conceptos Relacionados
Classification of Illness
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
Long-term Depression
Categories of Equilibrium
One of the categories of equilibrium is collinear equilibrium, which involves forces acting along a straight line. This type of equilibrium requires only one force equation in the direction of the forces, as the other equations are...
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Freezing Point Depression and Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
Depressants
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...

