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Updated: May 13, 2026

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Dirigirse a las células colinérgicas en un modelo de ratón de la enfermedad de Alzheimer: Validar un modelo

Szidónia Farkas1, Viktor Jasper2, Kinga Nyers-Marosi2

  • 1Molecular Neuroendocrinology Research Group, Institute of Physiology, University of Pécs, 7624 Pécs, Szigeti str. 12, Hungary; Laboratory of Behavioral and Stress Studies, Institute of Physiology, University of Pécs, 7624 Pécs, Szigeti str. 12, Hungary; Centre for Neuroscience, János Szentágothai Research Centre, University of Pécs, 7624 Pécs, Ifjúság str. 20, Hungary.

Experimental neurology
|February 12, 2026
PubMed
Resumen

Los investigadores desarrollaron un nuevo modelo de ratón de la enfermedad de Alzheimer (EA) con manipulación colinérgica funcional. Este modelo exhibe las características de la EA y los cambios de comportamiento, ayudando a los estudios preclínicos sobre los mecanismos colinérgicos de la EA.

Palabras clave:
La enfermedad de Alzheimer es la enfermedad de Alzheimer.El modelo animal es el modelo animal.Comportamiento Comportamiento Comportamiento.El sistema colinérgico es un sistemaInmunohistoquímica y inmunohistoquímica.Morfología Morfología Morfología.El transgenio transgénico.

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