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Updated: Feb 14, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

Validación Experimental de un Sensor y Estimulador Neural Implantable con RFID y sin Batería

Luís Eduardo Pedigoni Bulisani¹, Marco Antonio Herculano¹, Carolina Chen Pauris¹

¹Department of Research and Postgraduate Studies, Jundiaí Medical School, Rua Francisco Telles, 250, Vila Arens, Jundiaí 13202-550, SP, Brazil.

Sensors (Basel, Switzerland)

|February 13, 2026

Abstracto

Introduction:

Neurological injuries significantly impair quality of life by disrupting neural transmission. Traditional implantable stimulators often rely on internal batteries, which limit device longevity and necessitate repeated surgical interventions.

Objective:

This study presents the experimental validation of a battery-free, RFID-powered neural platform for peripheral nerve signal acquisition and stimulation, targeting TRL-6 validation.

Methods:

The prototype incorporates an adjustable analog front-end with gains up to 93 dB and a biphasic current-controlled stimulator. Validation was performed through benchtop testing, biological tissue assessments using porcine tissue, and functional in vivo trials in adult Wistar rats (n = 3) over a three-month period.

Results:

Benchtop evaluation confirmed gain accuracy with errors below 2.2 dB and precise stimulation timing. The system maintained a stable 3.3 V wireless power link through 20 mm of biological tissue using RFID. In vivo experiments indicated a 100% functional success rate (51/51 trials) in eliciting gross motor responses via wireless stimulation. Thermal safety was confirmed, with a maximum operating temperature of 28 °C, remaining well below physiological limits.

Conclusions:

The results demonstrate the functional feasibility of a battery-free, RFID-powered neural interface for wireless signal acquisition and stimulation, supporting system-level validation of this architecture.

Palabras clave:

sistemas alimentados por RFID dispositivos implantables sin batería medicina bioelectrónica interfaces neuronales neuroprótesis estimulación nerviosa periférica transferencia de energía inalámbrica

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