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Diagnóstico tardío de endocarditis infecciosa: análisis de una red de endocarditis
Shekhar Saha1, Benjamin Zauner1, Rainer Kaiser2,3
1Department of Cardiac Surgery, Ludwig Maximillian University of Munich, 80539 Munich, Germany.
Journal of clinical medicine
|February 13, 2026
Resumen
El diagnóstico tardío de la endocarditis infecciosa (EI) aumenta significativamente la mortalidad intrahospitalaria. El diagnóstico temprano de la EI es crucial para mejorar los resultados de los pacientes y las tasas de supervivencia.
Área de la Ciencia:
- Cardiología
- Enfermedades Infecciosas
- Investigación de Servicios de Salud
Sus antecedentes:
- El diagnóstico de endocarditis infecciosa (EI) presenta importantes desafíos clínicos.
- Comprender el impacto de los retrasos en el diagnóstico en los resultados de los pacientes con EI es fundamental.
Objetivo del estudio:
- Investigar una red de endocarditis y analizar las consecuencias del retraso en el diagnóstico de EI.
- Identificar los factores que influyen en el tiempo hasta el diagnóstico de EI y su asociación con la mortalidad.
Principales métodos:
- Revisión retrospectiva de 812 pacientes ingresados por EI entre enero de 2012 y diciembre de 2021.
- Diagnóstico confirmado según las directrices ESC/EACTS.
- Pacientes clasificados en grupos de diagnóstico temprano (ED, ≤7 días) y diagnóstico tardío (LD, >7 días).
Principales resultados:
- Un total de 707 pacientes tuvieron registros de tiempo de diagnóstico disponibles.
- El grupo LD exhibió un EuroSCORE II y un EndoSCORE significativamente más altos.
- El diagnóstico tardío se asoció de forma independiente con un aumento de la mortalidad intrahospitalaria, estancias más prolongadas en la UCI y en el hospital, y peores tasas de supervivencia a 1 y 5 años.
Conclusiones:
- El diagnóstico de EI está influenciado por varios factores, y los retrasos en el diagnóstico suponen un riesgo significativo.
- Un diagnóstico tardío de endocarditis infecciosa está relacionado de forma independiente con una mayor mortalidad intrahospitalaria.
- El diagnóstico temprano de EI se asocia con mejores resultados para los pacientes y tasas de supervivencia.
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