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Tiroiditis de Riedel secundaria a carcinoma papilar de tiroides: Reporte de un caso
Tongquan Zhao1, Shuqin Wang2, Min Zhang3
1Department of Surgery, People's Hospital of Rizhao City, Rizhao, China.
Medicine
|February 13, 2026
Resumen
La tiroiditis de Riedel (TR), una rara enfermedad relacionada con IgG4, puede simular cáncer de tiroides en las imágenes. Este caso resalta la importancia de una evaluación clinicopatológica integrada para evitar cirugías innecesarias para esta rara afección.
Área de la Ciencia:
- Endocrinología
- Patología
- Oncología
Sus antecedentes:
- La tiroiditis de Riedel (TR) es una manifestación rara de la enfermedad relacionada con inmunoglobulina G4 (IgG4-RD).
- Las IgG4-RDs se asocian con un mayor riesgo de malignidad.
- Las IgG4-RDs inducidas por malignidad son excepcionalmente raras, con documentación limitada en la literatura médica.
Objetivo del estudio:
- Reportar el primer caso documentado de tiroiditis de Riedel secundaria a carcinoma papilar de tiroides.
- Esclarecer la relación entre tumores malignos y IgG4-RDs.
- Enfatizar los desafíos diagnósticos y las implicaciones clínicas de esta rara asociación.
Principales métodos:
- Un hombre de 47 años presentó un nódulo en el cuello.
- El estudio diagnóstico incluyó examen histopatológico que reveló características consistentes con TR.
- El paciente se sometió a intervención quirúrgica (tiroidectomía y disección de ganglios linfáticos del cuello).
Principales resultados:
- El paciente fue diagnosticado con TR secundaria a carcinoma papilar de tiroides.
- La histopatología confirmó hiperplasia del tejido fibroso, folículos tiroideos atróficos e infiltración de células inflamatorias.
- El paciente se recuperó bien después de la cirugía y está en terapia con levotiroxina.
Conclusiones:
- La tiroiditis de Riedel puede presentarse con características de imagen que simulan malignidad tiroidea.
- Un alto índice de sospecha y una evaluación clinicopatológica integrada son cruciales para un diagnóstico preciso.
- Distinguir la TR de la malignidad es vital para prevenir el sobretratamiento y los procedimientos quirúrgicos innecesarios.
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