Video Experimental Relacionado
Updated: Feb 15, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
Resultados clínicos en glioblastoma recurrente con viroterapia oncolítica: una revisión
Feng Tang1,2, Zhen-Yuan Liu3,4, Jin-Zhou Yang3,4
1Brain Glioma Center, Department of Neurosurgery, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. tf172126@163.com.
Abstract:
Glioblastoma (GBM) is a highly aggressive and lethal form of brain cancer with limited treatment options, particularly for recurrent cases. Oncolytic virus (OV) therapy is a novel therapeutic strategy for recurrent GBM, leveraging its ability to selectively target and destroy malignant cells while sparing surrounding healthy tissue. Recent clinical trials have indicated that oncolytic virotherapy has an acceptable safety profile and the potential to enhance survival in recurrent GBM. For instance, CAN-3110, a Nestin-promoter-driven herpes simplex virus-1 (HSV-1), demonstrated a median overall survival of 14.9 months in patients with recurrent GBM, with HSV-1 seropositive patients achieving more prolonged survival (14.2 versus 7.8 months in seronegative patients). This review aims to synthesize the current evidence on clinical outcomes in patients with recurrent GBM receiving oncolytic virotherapy, with a specific focus on safety profiles, therapeutic efficacy, and survival outcomes.
Videos de Conceptos Relacionados
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:

