Financiación de los Institutos Nacionales de Salud para la Investigación de Tromboembolismo Venoso

Venous thromboembolism (VTE) is associated with approximately 100,000 deaths annually in the United States (U.S.). Progress in the prevention, diagnosis, treatment, and recovery of VTE depends on research funding. The National Institutes of Health (NIH), the world's largest funder of biomedical research, does not currently report VTE-specific funding in its annual categorical spending report. This study aimed to provide a descriptive analysis of NIH funding for VTE research over the past decade.

We conducted a search within the NIH RePORTER database for the years 2015 to 2024 using a string of VTE-related search terms. Grants were categorized as VTE research (yes/no) using a large language model prompted with predefined classification criteria. We tabulated annual NIH funding amounts, the number of VTE-related grants, and unique principal investigators. For 2023, the VTE research investment was compared to funding for heart disease and stroke, the leading causes of vascular mortality in the United States.

The search yielded 2,130 grants with complete data, of which 1,114 were classified as VTE research. When excluding renewal awards, 490 unique VTE grants were identified. Total inflation-adjusted NIH funding for VTE research was $42 million in 2015, peaked at $73 million in 2021, and totaled $67.1 million in 2024. In 2023, NIH funding per annual death was $2,765 for heart disease, $2,724 for stroke, and $639 for VTE.

The NIH investment in VTE research has increased over the past decade but remains disproportionately low relative to other major causes of vascular mortality in the United States.