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Updated: Feb 17, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

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Published on: February 26, 2013

Cierre percutáneo de la orejuela izquierda para el accidente cerebrovascular isquémico relacionado con la fibrilación

Kenshin Kawabata¹, Shuhei Egashira¹, Kyosuke Muramatsu¹

¹Department of Neurology, Toranomon Hospital.

Rinsho shinkeigaku = Clinical neurology

|February 15, 2026

Abstract:

A 79-year-old woman developed weakness in her right upper and lower limbs despite appropriate therapy with edoxaban 30 ‍mg once daily for non-valvular atrial fibrillation (CHA2DS2-VASc score of 7, HAS-BLED score of 3). Brain MRI revealed an acute infarct in the territory of the left long insular artery or white-matter medullary artery. Transesophageal echocardiogram showed spontaneous echo contrast and reduced flow velocities in the left atrial appendage (LAA), leading to a diagnosis of cardioembolic stroke. Edoxaban was continued, and the patient underwent percutaneous left atrial appendage occlusion (LAAO). Her clinical course was uncomplicated by recurrent ischemic stroke or device-related thrombosis. For patients with atrial fibrillation-related ischemic stroke despite anticoagulation, adding LAAO to ongoing anticoagulation may be an effective option for secondary prevention.

Palabras clave:

fibrilación auricular accidente cerebrovascular isquémico relacionado con la fibrilación auricular a pesar de la anticoagulación anticoagulación oral directa oclusión percutánea de la orejuela izquierda

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