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Updated: Feb 19, 2026
Author Spotlight: Advancing Reproductive Immunology with a Protocol for the Quantitative Evaluation of Endometrial Immune Cells
Published on: October 13, 2023
Soluciones basadas en precisión para la endometriosis: Integración de la inmunómica y estrategias de
Hongyuan Li1, Muyao Yang1, Han Zhu1
1Department of Medical Cell Biology and Genetics, School of Basic Medical Sciences, Southwest Medical University, Luzhou 646000, Sichuan, China.
Abstract:
Endometriosis (EMs) is an estrogen-dependent, chronic inflammatory disorder characterized by immune microenvironment dysregulation, a critical factor in its pathogenesis. Despite existing therapies, limitations persist, highlighting the urgent need for innovative treatment strategies. This review explores the roles of immune cell dysfunction, immune evasion, and immunomics in EMs. We emphasize the potential of immune-modulating therapies, anti-inflammatory agents, targeted interventions, and epigenetic modulators in advancing treatment options. Additionally, we propose a drug screening framework based on the immune microenvironment. Integrating these insights with drug repositioning approaches promises to drive EMs therapy toward more tailored, precision-based solutions.
