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Revisión de Agentes Adrenérgicos Alfa-2 Implicados en el Trastorno por Uso de Opioides

Audrey Hannum1, Isabella Spano1, Edward Ofori1

  • 1Ohio Northern University Department of Pharmaceutical and Biomedical Sciences, Rudolph H. Raabe College of Pharmacy, Ohio Northern University, Ada, Ohio 45810, United States.

ACS chemical neuroscience
|February 18, 2026
PubMed
Resumen

El trastorno por uso de opioides es una crisis, ahora complicada por el fentanilo adulterado con xilazina y medetomidina. Los medicamentos actuales de reversión de sobredosis son ineficaces contra estos agonistas alfa-2.

Palabras clave:
TRASTORNO POR USO DE OPIOIDESadrenérgicoagonista adrenérgico alfa-2clonidinamedetomidinasobredosis de opioidestrastorno por uso de opioidessalud públicaxilazinatoxicidad del agonista alfa-2

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