Video Experimental Relacionado

Updated: Apr 24, 2026

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications
09:39

Drug-induced Sensitization of Adenylyl Cyclase: Assay Streamlining and Miniaturization for Small Molecule and siRNA Screening Applications

Published on: January 27, 2014

13.1K

Interfaces de ingeniería en biosensores de Rac1 y Cdc42 mejoran la sensibilidad y reducen la perturbación celular

Daniel J Marston1,2, Ellen C O'Shaughnessy1,3, Timothy M Jacobs4

  • 1Department of Pharmacology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Molecular biology of the cell
|February 18, 2026
PubMed
Resumen

Los biosensores fluorescentes diseñados minimizan la interferencia con las actividades celulares. Los nuevos diseños reducen las interacciones no deseadas de proteínas, lo que permite un seguimiento más preciso de la dinámica de proteínas en células vivas.

Palabras clave:
biosensores fluorescentesRac1Cdc42FRETcélulas vivasimagenologíaactividad proteicaperturbación celular

Más Videos Relacionados

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology09:39

Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology

Published on: March 31, 2022

3.7K
Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow08:58

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow

Published on: October 17, 2025

701

Videos de Conceptos Relacionados

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
86