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Dolichocolon tipo 1 como comorbilidad potencial en niños con enfermedad de Crohn perianal
Richard Kellermayer1,2,3, Réka G Szigeti4, Marla Sammer5
1Division of Pediatric Gastroenterology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. kellerma@bcm.edu.
Background:
Perianal Crohn's disease (PCD) represents one of the most severe and refractory forms of pediatric inflammatory bowel disease (IBD). Constipation and colonic redundancy, particularly type 1 dolichocolon (T1-DC), may increase distal rectosigmoid pressure, and exacerbate perianal pathology. We hypothesized that T1-DC is more common in children with PCD than in those with uncomplicated ileocolonic Crohn's disease (CD) or non-IBD controls.
Methods:
Retrospective electronic medical record search was performed. DC type was determined radiographically using established criteria, focusing on T1- and T2-DC. Constipation history was abstracted from medical records under IRB-approved protocols.
Results:
Twenty consecutive children with PCD [penetrating (B3p) or inflammatory (B1p)] were compared to 20 children with non-complicated ileocolonic CD (L3/B1) and 30 non-IBD trauma controls. DC was significantly more prevalent in PCD than in ileocolonic CD or controls (p < 0.001), primarily due to T1-DC. The associations persisted (p < 0.03) in PCD patients without a history of constipation.
Conclusions:
Rectosigmoid redundancy (T1-DC) may represent an underrecognized anatomic co-morbidity in children with PCD, contributing to increased distal pressure and susceptibility to perianal complications. Identification of T1-DC could inform surgical decision-making and postoperative management. Targeted approaches-such as segmental resection during stoma reversal, structured bowel regimens, physical activity, and pelvic-floor biofeedback-may help reduce recurrence risk. Prospective studies are needed to define the mechanistic role of colonic redundancy in the pathogenesis of PCD.
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