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Updated: Feb 20, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
Resultados a largo plazo de la reparación de la válvula aórtica en niños después de la infancia
Michael Z L Zhu1, Igor E Konstantinov2, Tyson A Fricke1
1Department of Cardiac Surgery, The Royal Children's Hospital, Melbourne, Australia; Department of Paediatrics, The University of Melbourne, Melbourne, Australia; Heart Research Group, Murdoch Children's Research Institute, Melbourne, Australia.
Background:
We evaluated the long-term outcomes of children who underwent aortic valve (AoV) repair after infancy.
Methods:
A retrospective, single institutional study of all patients aged ≥1 year old who underwent primary AoV repair between 1980 and 2024 was performed (N=326).
Results:
Median age at AoV repair was 9.4 (IQR,4.8-14.2) years. Repair was achieved without patch material in 49.7% (162/326) of patients. Early mortality was 0.61% (2/326). Late death was 1.85%, (6/324). Median follow-up was 9.04 (IQR,3.4-16.6) years. Kaplan-Meier estimated survival at 10, 15 and 20 years was 98.4%, 97.9% and 94.9%. Freedom from AoV reoperation at 5, 10, 15 and 20 years was 85.6%, 74.1%, 59.1% and 55.0%. Freedom from AoV replacement (AVR) at 5, 10, 15 and 20 years was 92.2%, 79.5%, 65.7% and 61.7%. Twenty-year freedom from prosthetic AVR was 79.1%. During follow-up, 83 patients (25.5%, 83/326) underwent 101 AoV reoperations including 26 redo repairs, 35 Ross operations and 40 prosthetic AVRs. Independent risk factors for AVR were previous balloon aortic valvuloplasty [HR:2.34 (95%CI 1.27-4.30), p=0.006], AoV repair requiring CardioCel patch [HR:4.30 (95%CI 1.89-9.74), p<0.001] and subcommissural annuloplasty [HR:3.37 (95%CI 1.56-7.28), p=0.002].
Conclusion:
In children who underwent AoV repair after infancy, 15-year freedom from AoV reoperation or replacement was 59% and 66% respectively, with most undergoing either a subsequent Ross operation or redo AoV repair. Thus, in the lifelong management of AoV disease in children after infancy, a strategy of initial AoV repair allowed the majority of patients to progress through childhood without further AoV surgery and defers prosthetic AVR well into adult life.
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