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Updated: Feb 20, 2026

Urethral Stricture Induction Followed by Buccal Mucosa Graft Urethroplasty in a Rat Model
Published on: April 28, 2023
Uretroplastia de ensanchamiento por incrustación dorsal con injerto mucoso de labio para fallos de hipospadias
Zhongying Han1, Ji Li1, Qian Zhang1
1Department of Pediatric Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
Abstract:
We explored a "widening surgery" utilizing dorsal stricturotomy and lip mucosal graft inlay for post-pubertal long-segment urethral strictures (LSS). In 8 adolescents (median age 16.3 years), 6 underwent single-stage and 2 underwent planned two-stage repair due to infection. At a median follow-up of 39 months, the primary success rate was 87.5 % (7/8). One fistula occurred and was successfully repaired. Median maximum urinary flow (Qmax) improved from 4.4 to 24.5 ml/s. This study suggests dorsal inlay widening urethroplasty is a feasible strategy for complex LSS, preserving the urethral plate, though larger validation studies are required.

