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Updated: Feb 20, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems

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Impulsar el Cambio Mediante el Uso de Evidencia

Barbara R Chapman¹, Melissa De Los Santos

¹Barbara Chapman is an associate professor and the founding faculty program coordinator of the Psychiatric Mental Health Nurse Practitioner Program at the University of North Texas Health Science Center's College of Nursing in Fort Worth, TX. Melissa De Los Santos is a professor in the Vocational Nursing Program, Eastview Campus of Austin Community College in Austin, TX. Contact author: Barbara Chapman, bchapman0430@gmail.com. The authors have disclosed no potential conflicts of interest, financial or otherwise.

The American journal of nursing

|February 19, 2026

Resumen

Este estudio explora la aplicación práctica de conceptos científicos. Detalla el proceso de traducción de conocimientos teóricos en resultados tangibles y estrategias efectivas.

Área de la Ciencia:

Ciencia de la implementación
Ciencias aplicadas

Sus antecedentes:

Comprender los desafíos en la traducción de la investigación a la práctica.
Identificar los factores clave que influyen en la implementación exitosa.

Objetivo del estudio:

Esbozar un marco para una implementación efectiva.
Proporcionar orientación práctica para aplicar el conocimiento teórico.

Principales métodos:

Revisión de literatura sobre estrategias de implementación.
Análisis de casos de proyectos exitosos.
Desarrollo de un modelo de implementación práctica.

Principales resultados:

Se identificaron factores críticos de éxito para la implementación.
Se demostró la efectividad de un enfoque estructurado.
Se proporcionaron ideas prácticas para los profesionales.

Conclusiones:

La implementación efectiva requiere una planificación y ejecución cuidadosas.
Un enfoque sistemático aumenta la probabilidad de resultados exitosos.
El estudio ofrece un recurso valioso para mejorar las prácticas de implementación.

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